 |
|
|
Аульченко Юрий Сергеевич, д. б. н.
|
Персональная информацияРабочий адрес
Г. Новосибирск, пр. Академика Лаврентьева д. 10, Россия
Год рождения
1975
Образование
ФЕН НГУ, 1992-1997 – студент очного отделения (биология)
ИЦиГ СО РАН, 1997–2000 – аспирант (генетика)
Область научных интересов
Статистическая геномика, высокопроизводительные вычисления
Редакционная и издательская деятельность
Член редколлегии Вавиловского журнала генетики и селекции
Идентификаторы
Scopus Author ID: 6603626351
http://orcid.org/0000-0002-7899-1575
РИНЦ ID: 88429
Личная страница
http://mga.bionet.nsc.ru/~yurii/
Публикации
| 2023 |
Bidirectional Mendelian Randomization Study of Personality Traits Reveals a Positive Feedback Loop Between Neuroticism and Back Pain
Elgaeva EE, Williams FMK, Zaytseva OO, Freidin MB, Aulchenko YS, Suri P, Tsepilov YA
[J PAIN]
|
|
Development and Replication of a Genome-Wide Polygenic Risk Score for Chronic Back Pain
Tsepilov YA, Elgaeva EE, Nostaeva AV, Compte R, Kuznetsov I, Karssen LC, Freidin MB, Suri P, Williams FMK, Aulchenko YS
[J. Pers. Med]
|
|
Evidence of causal effects of blood pressure on back pain and back pain on type II diabetes provided by a bidirectional Mendelian randomization study
Suri P, Elgaeva EE, Williams FMK, Freidin MB, Zaytseva OO, Aulchenko YS, Tsepilov YA
[SPINE J]
|
|
Genetic control of N-glycosylation of human blood plasma proteins
S.Zh. Sharapov, A.N. Timoshchuk, Y.S. Aulchenko
[Vavilov journal of genetics and breeding]
|
| 2022 |
Noncoding rare variants in PANX3 are associated with chronic back pain
Nadezhda M Belonogova, Anatoly V Kirichenko, Maxim B Freidin, Frances M K Williams, Pradeep Suri, Yurii S Aulchenko, Tatiana I Axenovich, Yakov A Tsepilov
[PAIN]
|
|
Causal effects of psychosocial factors on chronic back pain: a bidirectional Mendelian randomisation study
Frances M K Williams, Elizaveta E Elgaeva, Maxim B Freidin, Olga O Zaytseva, Yurii S Aulchenko, Yakov A Tsepilov, Pradeep Suri
[EUR SPINE J]
|
|
Association Between Human Gut Microbiome and N-Glycan Composition of Total Plasma Proteome
Vyacheslav A. Petrov, Sodbo Zh. Sharapov, Lev Shagam, Arina V. Nostaeva, Marija Pezer, Dalin Li, Maja Hanić, Dermot McGovern, Edouard Louis, Souad Rahmouni, Gordan Lauc, Michel Georges, and Yurii S. Aulchenko
[Frontiers in Microbiology]
|
|
Genetic regulation of post-translational modification of two distinct proteins
Arianna Landini, Irena Trbojević-Akmačić, Pau Navarro, Yakov A Tsepilov, Sodbo Z Sharapov, Frano Vučković, Ozren Polašek, Caroline Hayward, Tea Petrović, Marija Vilaj, Yurii S Aulchenko, Gordan Lauc, James F Wilson, Lucija Klarić
[NAT COMMUN]
|
|
A protocol for recruiting and analyzing the disease-oriented Russian disc degeneration study (RuDDS) biobank for functional omics studies of lumbar disc degeneration
Olga N. Leonova, Elizaveta E. Elgaeva, Tatiana S. Golubeva, Alexey V. Peleganchuk, Aleksandr V. Krutko, Yurii S. Aulchenko, Yakov A. Tsepilov
[PloS One]
|
|
Method for the Isolation of “RNA-seq-Quality” RNA from Human Intervertebral Discs after Mortar And Pestle Homogenization
Artemii A. Ivanov, Olga N. Leonova, Daniil S. Wiebe, Alexsandr V. Krutko, Mariya M. Gridina, Veniamin S. Fishman, Yurii S. Aulchenko, Yakov A. Tsepilov, Tatiana S. Golubeva
[Cells]
|
|
Платформа GWAS-MAP|ovis для хранения и анализа результатов полногеномных ассоциативных исследований овец
А. В. Кириченко, А. С. Злобин, Т. И. Шашкова, Н. А. Волкова, Б. С. Иолчиев, В. А. Багиров, П. М. Бородин, Л. С. Карссен, Я. А. Цепилов, Ю. С. Аульченко
[Vavilov journal of genetics and breeding]
|
| 2021 |
Investigation of the causal relationships between human IgG N-glycosylation and 12 common diseases associated with changes in the IgG N-glycome
Olga O Zaytseva, Sodbo Zh Sharapov, Marcus Perola, Tonu Esko, Arianna Landini, Caroline Hayward, James F Wilson, Gordan Lauc, Yurii S Aulchenko, Lucija Klarić, Yakov A Tsepilov
[HUM MOL GENET]
|
|
Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR
Scherer M, Gasparoni G, Rahmouni S, Shashkova T, Arnoux M, Louis E, Nostaeva A, Avalos D, Dermitzakis ET, Aulchenko YS, Lengauer T, Lyons PA, Georges M, Walter J
[EPIGENET CHROMATIN]
|
|
Genome-wide association studies of low back pain and lumbar spinal disorders using electronic health record data identify a locus associated with lumbar spinal stenosis
Suri P, Stanaway IB, Zhang Y, Freidin MB, Tsepilov YA, Carrell DS, Williams FMK, Aulchenko YS, Hakonarson H, Namjou B, Crosslin DR, Jarvik GP, Lee MT
[PAIN]
|
|
Multivariate genome-wide analysis of immunoglobulin G N-glycosylation identifies new loci pleiotropic with immune function.
Shadrina AS, Zlobin AS, Zaytseva OO, Klarić L, Sharapov SZ, D Pakhomov E, Perola M, Esko T, Hayward C, Wilson JF, Lauc G, Aulchenko YS, Tsepilov YA
[HUM MOL GENET]
|
|
Nontrivial Replication of Loci Detected by Multi-Trait Methods.
Ning Z, Tsepilov YA, Sharapov SZ, Wang Z, Grishenko AK, Feng X, Shirali M, Joshi PK, Wilson JF, Pawitan Y, Haley CS, Aulchenko YS, Shen X
[Frontiers in Genetics]
|
|
Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain.
Rahman MS, Winsvold BS, Chavez Chavez SO, Børte S, Tsepilov YA, Sharapov SZ; HUNT All-In Pain, Aulchenko YS, Hagen K, Fors EA, Hveem K, Zwart JA, van Meurs JB, Freidin MB, Williams FM.
[ANN RHEUM DIS]
|
|
PheLiGe: an interactive database of billions of human genotype-phenotype associations
Shashkova TI, Pakhomov ED, Gorev DD, Karssen LC, Joshi PK, Aulchenko YS
[NUCLEIC ACIDS RES]
|
|
Quantitative Genetics of Human Protein N-Glycosylation
Krištić J, Sharapov SZ, Aulchenko YS
[ADV EXP MED BIOL]
|
|
The limits of normal approximation for adult height
Sergei A. Slavskii
Ivan A. Kuznetsov
Tatiana I. Shashkova
Georgii A. Bazykin
Tatiana I. Axenovich
Fyodor A. Kondrashov
Yurii S. Aulchenko
[EUR J HUM GENET]
|
| 2020 |
Sex- and age-specific genetic analysis of chronic back pain
Freidin M.B., Tsepilov Y.A., Stanaway I.B., Meng W., Hayward C., Smith B.H., Khoury S., Parisien M., Bortsov A., Diatchenko L., Borte S., Winsvold BS, Brumpton BM, Zwart JA, Aulchenko Y.S., Suri P., Williams F.M.K., HUNT All-In Pain
[PAIN]
|
|
Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases
Klarić, Lucija
Tsepilov, Yakov A.
Stanton, Chloe M.
Mangino, Massimo
Sikka, Timo Tõnis
Esko, Tõnu
Pakhomov, Eugene
Salo, Perttu
Deelen, Joris
McGurnaghan, Stuart J.
Keser, Toma
Vučković, Frano
Ugrina, Ivo
Krištić, Jasminka
Gudelj, Ivan
Štambuk, Jerko
Plomp, Rosina
Pučić-Baković, Maja
Pavić, Tamara
Vilaj, Marija
Trbojević-Akmačić, Irena
Drake, Camilla
Dobrinić, Paula
Mlinarec, Jelena
Jelušić, Barbara
Richmond, Anne
Timofeeva, Maria
Grishchenko, Alexander K.
Dmitrieva, Julia
Bermingham, Mairead L.
Sharapov, Sodbo Zh.
Farrington, Susan M.
Theodoratou, Evropi
Uh, Hae-Won
Beekman, Marian
Slagboom, Eline P.
Louis, Edouard
Georges, Michel
Wuhrer, Manfred
Colhoun, Helen M.
Dunlop, Malcolm G.
Perola, Markus
Fischer, Krista
Polasek, Ozren
Campbell, Harry
Rudan, Igor
Wilson, James F.
Zoldoš, Vlatka
Vitart, Veronique
Spector, Tim
Aulchenko, Yurii S.
Lauc, Gordan
Hayward, Caroline
[Sci Advances]
|
|
Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions
Tsepilov Y. A., Freidin M. B., Shadrina A. S., Sharapov S. Z., Elgaeva E. E., van Zundert J., Karssen L. С., Suri P., Williams F. M. K., Aulchenko Y. S.
[Commun. biolog.]
|
|
Prioritization of causal genes for coronary artery disease based on cumulative evidence from experimental and in silico studies
Shadrina A. S., Shashkova T. I., Torgasheva A. A., Sharapov S. Z., Klarić L., Pakhomov E. D., Alexeev D. G., Wilson J. F., Tsepilov Y. A., Joshi P. K., Aulchenko Y. S.
[SCI REP-UK]
|
|
Replication of 15 loci involved in human plasma protein N-glycosylation in 4,802 samples from four cohorts
Sharapov SZ, Shadrina AS, Tsepilov YA, Elgaeva EE, Tiys ES, Feoktistova SG, Zaytseva OO, Vuckovic F, Cuadrat R, Jäger S, Wittenbecher C, Karssen LC, Timofeeva M, Tillin T, Trbojević-Akmačić I, Štambuk T, Rudman N, Krištić J, Šimunović J, Momčilović A, Vilaj M, Jurić J, Slana A, Gudelj I, Klarić T, Puljak L, Skelin A, Kadić AJ, Van Zundert J, Chaturvedi N, Campbell H, Dunlop M, Farrington SM, Doherty M, Dagostino C, Gieger C, Allegri M, Williams F, Schulze MB, Lauc G, Aulchenko YS.
[GLYCOBIOLOGY]
|
|
The GWAS-MAP platform for aggregation of results of genome-wide association studies and the GWAS-MAP|homo database of 70 billion genetic associations of human traits
Shashkova T.I., Gorev D.D., Pakhomov E.D., Shadrina A.S., Sharapov S.Z., Tsepilov Y.A., Karssen L.C., Aulchenko Y.S.
[Vavilov journal of genetics and breeding]
|
|
The New Coronavirus COVID-19 Infection
Bevova M.R., Netesov S.V., Aulchenko Y.S.
[MOL GENET MICROBIOL+]
|
| 2019 |
Defining the genetic control of human blood plasma N-glycome using genome-wide association study
Sharapov S, Tsepilov Y, Klaric L, Mangino M, Thareja G, Shadrina A, Simurina M, Dagostino C, Dmitrieva J, Vilaj M, Vuckovic F, Pavic T, Stambuk J, Trbojevic-Akmacic I, Kristic J, Simunovic J, Momcilovic A, Campbell H, Doherty M, Dunlop M, Farrington S, Pucic-Bakovic M, Gieger C, Allegri M, Louis E, Georges M, Suhre K, Spector T, Williams F, Lauc G, Aulchenko Y
[HUM MOL GENET]
|
|
Examining causal effects of body mass index on back pain: a Mendelian randomization study
Elizaveta E. Elgaeva, Yakov Tsepilov, Maxim B. Freidin, Frances M. K. Williams, Yurii Aulchenko, Pradeep Suri
[EUR SPINE J]
|
|
Identification of 12 genetic loci associated with human healthspan
Zenin A, Tsepilov Y, Sharapov S, Getmantsev E, Menshikov LI, Fedichev PO, Aulchenko Y
[Commun. biolog.]
|
|
Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals
Maxim B. Freidin, Yakov A. Tsepilov, Melody Palmer, Lennart C. Karssen, CHARGE Musculoskeletal Working Group, Pradeep Suri, Yurii S. Aulchenko, Frances M.K. Williams
[PAIN]
|
| 2018 |
A network-based conditional genetic association analysis of the human metabolome
Y A Tsepilov, S Z Sharapov, O O Zaytseva, J Krumsek, C Prehn, J Adamski, G Kastenmüller, R Wang-Sattler, K Strauch, C Gieger, Y S Aulchenko
[GigaScience]
|
|
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain
Pradeep Suri, Melody R. PalmerID, Yakov A. Tsepilov, Maxim B. Freidin,Cindy G. Boer, Michelle S. Yau, Daniel S. Evans, Andrea Gelemanovic,Traci M. Bartz, Maria Nethander, Liubov Arbeeva, Lennart Karssen, Tuhina Neogi, Archie Campbell, Dan Mellstrom, Claes Ohlsson, Lynn M. Marshall, Eric Orwoll, Andre Uitterlinden, Jerome I. Rotter, Gordan Lauc, Bruce M. Psaty, Magnus K. Karlsson, Nancy E. Lane, Gail P. Jarvik, Ozren Polasek, Marc Hochberg, Joanne M. Jordan, Joyce B. J. Van Meurs, Rebecca Jackson, Carrie M. Nielson, Braxton D. Mitchell, Blair H. Smith, Caroline Hayward, Nicholas L. Smith, Yurii S. Aulchenko, Frances M. K. Williams
[PLOS GENET]
|
|
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
Momozawa Y, Dmitrieva J, Théâtre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Amininejad L, Bouma G, Hoentjen F, Löwenberg M, Oldenburg B, Pierik MJ, Vander Meulen-de Jong AE, Janneke van der Woude C,Visschedijk MC, International IBD Genetics Consortium, Lathrop M, Hugot JP,Weersma RK, De Vos M, Franchimont D, Vermeire S, Kubo M, Louis E, Georges M
[NAT COMMUN]
|
|
Plasma N-glycome composition associates with chronic low back pain
Trbojevic-Akmacic I, Vuckovic F, Vilaj M, Skelin A, Karssen LC, Kristic J, Juric J, Momcilovic A, Simunovic J, Mangino M, De Gregori M, Marchesini M, Dagostino C, Stambuk J, Novokmet M, Rauck R, Aulchenko YS, Primorac D, Kapural L, Buyse K, Mesotten D, Williams FMK, van Zundert J, Allegri M, Lauc G
[BBA-GEN SUBJECTS]
|
| 2017 |
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation
Shen, Xia
Klarić, Lucija
Sharapov, Sodbo
Mangino, Massimo
Ning, Zheng
Wu, Di
Trbojević-Akmačić, Irena
Pučić-Baković, Maja
Rudan, Igor
Polašek, Ozren
Hayward, Caroline
Spector, Timothy D.
Wilson, James F.
Lauc, Gordan
Aulchenko, Yurii S.
[NAT COMMUN]
|
|
Population specific analysis of Yakut exomes
AS Zlobin, S Sh Sharapov, VP Guryev, MR Bevova, YA Tsepilov, TM Sivtseva, UA Boyarskih, EA Sokolova, YS Aulchenko, ML Filipenko, VL Osakovsky
[Doklady Biochemistry and Biophysics]
|
|
Популяционно-генетический анализ экзомов представителей якутского этноса.
А. C. Злобин, С. Ж. Шарапов, В. П. Гурьев, М. P. Бевова, Я. А. Цепилов, Т. М. Сивцева, У. А. Боярских, Е. А. Соколова, Ю. С. Аульченко, М. Л. Филипенко, В. Л. Осаковский.
[Doklady Akademii Nauk]
|
| 2016 |
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease
Ventham N.T., Kennedy N.A., Adams A.T., Kalla R., Heath S., O'Leary K.R., Drummond H., Wilson D.C., Gut I.G., Nimmo E.R., Satsangi J., Lauc G., Campbell H., McGovern D.P.B., Annese V., Zoldoš V., Permberton I.K., Wuhrer M., Kolarich D., Fernandes D.L., Theorodorou E., Merrick V., Spencer D., Gardner R.A., Doran R., Shubhakar A., Boyapati R., Rudan I., Lionetti P., Akmačić I.T., Krištić J., Vučković F., Štambuk J., Novokmet M., Pučić-Baković M., Gornik O., Andriulli A., Cantoro L., Sturniolo G., Fiorino G., Manetti N., Latiano A., Kohn A., D'Incà R., Danese S., Arnott I.D., Noble C.L., Lees C.W., Shand A.G., Ho G.-T., Dunlop M.G., Murphy L., Gibson J., Evenden L., Wrobel N., Gilchrist T., Fawkes A., Kammeijer G.S.M., Clerc F., De Haan N., Vojta A., Samaržija I., Markulin D., Klasić M., Dobrinić P., Aulchenko Y., Van Den Heuve T., Jonkers D., Pierik M., Vatn S., Ricanek P., Jahnsen J., You P., Sølvernes J., Frengen A.B., Tannæs T.M., Moen A.E.F., Dahl F.A., Lindstrøm J.C., Ekeland G.S., Detlie T.E., Keita A.V., Söderholm J.D., Hjortswang H., Halfvarson J., Bergemalm D., Gomollón F., D'Amato M., Törkvist L., Hjelm F., Gullberg M., Nordberg N., Ocklind A., Pettersson E., Ekman D., Sundell M., Modig E., Veillard A.-C., Schoemans R., Poncelet D., Sabatel C., Gut M., Bayes M., Casén C., Lindahl T., Ciemniejewska E., Vatn M.H.
[NAT COMMUN]
|
|
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
Zhernakova A, Kurilshikov A, Bonder MJ, Tigchelaar EF, Schirmer M, Vatanen T, Mujagic Z, Vila AV, Falony G, Vieira-Silva S, Wang J, Imhann F, Brandsma E, Jankipersadsing SA, Joossens M, Cenit MC, Deelen P, Swertz MA; LifeLines cohort study, Weersma RK, Feskens EJ, Netea MG, Gevers D, Jonkers D, Franke L, Aulchenko YS, Huttenhower C, Raes J, Hofker MH, Xavier RJ, Wijmenga C, Fu J.
[SCIENCE]
|
|
The Association Between Glycosylation of Immunoglobulin G and Hypertension: A Multiple Ethnic Cross-Sectional Study
Wang Y, Klarić L, Yu X, Thaqi K, Dong J, Novokmet M, Wilson J, Polasek O, Liu Y, Krištić J, Ge S, Pučić-Baković M, Wu L, Zhou Y, Ugrina I, Song M, Zhang J, Guo X, Zeng Q, Rudan I, Campbell H, Aulchenko Y, Lauc G, Wang W.
[Medicine (Baltimore)]
|
|
The GenABEL Project for statistical genomics
Karssen LC, van Duijn CM, Aulchenko YS
[F1000Res]
|
|
The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers: a new canine model for copper-metabolism disorders
Fieten H, Gill Y, Martin AJ, Concilli M, Dirksen K, van Steenbeek FG, Spee B, van den Ingh TS, Martens EC, Festa P, Chesi G, van de Sluis B, Houwen RH, Watson AL, Aulchenko YS, Hodgkinson VL, Zhu S, Petris MJ, Polishchuk RS, Leegwater PA, Rothuizen J
[DIS MODEL MECH]
|
| 2015 |
A genome wide association study links glutamate receptor pathway to sporadic creutzfeldt-jakob disease risk.
Sanchez-Juan P, Bishop MT, Kovacs GG, Calero M, Aulchenko YS, Ladogana A, Boyd A, Lewis V, Ponto C, Calero O, Poleggi A, Carracedo Á, van der Lee SJ, Ströbel T, Rivadeneira F, Hofman A, Haïk S, Combarros O, Berciano J, Uitterlinden AG, Collins SJ, Budka H, Brandel JP, Laplanche JL, Pocchiari M, Zerr I, Knight RS, Will RG, van Duijn CM.
[PloS One]
|
|
Inflammatory bowel disease associates with pro-inflammatory potential of the IgG glycome.
Irena Trbojević Akmačić, Nicholas T Ventham, Evropi Theodoratou, Frano Vučković, Nicholas A Kennedy, Jasminka Krištić, Elaine R Nimmo, Rahul Kalla, Hazel Drummond, Jerko Štambuk, Malcolm G Dunlop, Mislav Novokmet, Yurii Aulchenko, Olga Gornik, IBD-BIOM consortium, Harry Campbell, Maja Pučić-Baković, Jack Satsangi, Gordan Lauc
[INFLAMM BOWEL DIS]
|
|
NON-ADDITIVE EFFECTS OF GENES IN HUMAN METABOLOMICS
Tsepilov Y.A, Shin S., Soranzo N., Spector TD., Prehn C., Adamski J., Kastenmüller G., Wang-Sattler R., Strauch K., Gieger C., Aulchenko Y.S., Ried J.S.
[GENETICS]
|
|
ГЕНЕТИКА РАССЕЯННОГО СКЛЕРОЗА СЕГОДНЯ
СОКОЛОВА Е.А., БОЯРСКИХ У.А., АУЛЬЧЕНКО Ю.С., ФИЛИПЕНКО М.Л.
[Успехи современной биологии]
|
| 2014 |
Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological research.
Huffman JE, Pučić-Baković M, Klarić L, Hennig R, Selman MH, Vučković F, Novokmet M, Krištić J, Borowiak M, Muth T, Polašek O, Razdorov G, Gornik O, Plomp R, Theodoratou E, Wright AF, Rudan I, Hayward C, Campbell H, Deelder AM, Reichl U, Aulchenko YS, Rapp E, Wuhrer M, Lauc G.
[Mol Cell Proteomics.]
|
|
Glycans are a novel biomarker of chronological and biological ages.
Krištić J, Vučković F, Menni C, Klarić L, Keser T, Beceheli I, Pučić-Baković M, Novokmet M, Mangino M, Thaqi K, Rudan P, Novokmet N, Sarac J, Missoni S, Kolčić I, Polašek O, Rudan I, Campbell H, Hayward C, Aulchenko Y, Valdes A, Wilson JF, Gornik O, Primorac D, Zoldoš V, Spector T, Lauc G.
[J Gerontol A Biol Sci Med Sci]
|
|
High-Performance Mixed Models Based Genome-Wide Association Analysis with omicABEL software
Fabregat-Traver D., Sharapov S.Z., Hayward C., Rudan I., Campbell H., Aulchenko Y., Bientinesi P.
[F1000Res]
|
|
Solving sequences of generalized least-squares problems on multi-threaded architectures
Fabregat-Traver D, Aulchenko Y, Bientinesi P
[APPL MATH COMPUT]
|
| 2013 |
DEVELOPMENT AND APPLICATION OF GENOMIC CONTROL METHODS FOR GENOME-WIDE ASSOCIATION STUDIES USING NON-ADDITIVE MODELS
Yakov A. Tsepilov Janina S. Ried Konstantin Strauch Harald Grallert Cornelia M. van Duijn Tatiana I. Axenovich Yurii S. Aulchenko
[PloS One]
|
|
Association of SNPs of CD40 gene with multiple sclerosis in Russians
Sokolova EA, Malkova NA, Korobko DS, Rozhdestvenskii AS, Kakulya AV, Khanokh EV, Delov RA, Platonov FA, Popova TY, Aref' eva EG, Zagorskaya NN, Alifirova VM, Titova MA, Smagina IV, El' chaninova SA, Popovtseva AV, Puzyrev VP, Kulakova OG, Tsareva EY, Favorova OO, Shchur SG, Lashch NY, Popova NF, Popova EV, Gusev EI, Boyko AN, Aulchenko YS, Filipenko ML.
[PloS One]
|
|
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers
Lauc G, Huffman JE, Pučić M, Zgaga L, Adamczyk B, Mužinić A, Novokmet M, Polašek O, Gornik O, Krištić J, Keser T, Vitart V, Scheijen B, Uh HW, Molokhia M, Patrick AL, McKeigue P, Kolčić I, Lukić IK, Swann O, van Leeuwen FN, Ruhaak LR, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, de Craen AJ, Deelder AM, Zeng Q, Wang W, Hastie ND, Gyllensten U, Wilson JF, Wuhrer M, Wright AF, Rudd PM, Hayward C, Aulchenko Y, Campbell H, Rudan I.
[PLOS GENET]
|
|
Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions
Amin N, Hottenga JJ, Hansell NK, Janssens AC, de Moor MH, Madden PA, Zorkoltseva IV, Penninx BW, Terracciano A, Uda M, Tanaka T, Esko T, Realo A, Ferrucci L, Luciano M, Davies G, Metspalu A, Abecasis GR, Deary IJ, Raikkonen K, Bierut LJ, Costa PT, Saviouk V, Zhu G, Kirichenko AV, Isaacs A, Aulchenko YS, Willemsen G, Heath AC, Pergadia ML, Medland SE, Axenovich TI, de Geus E, Montgomery GW, Wright MJ, Oostra BA, Martin NG, Boomsma DI, van Duijn CM.
[EUR J HUM GENET]
|
|
Region-based association analysis of human quantitative traits in related individuals
Belonogova NM, Svishcheva GR, van Duijn CM, Aulchenko YS, Axenovich TI.
[PloS One]
|
| 2012 |
A genome-wide linkage study of individuals with high scores on NEO personality traits.
Amin N, Schuur M, Gusareva ES, Isaacs A, Aulchenko YS, Kirichenko AV, Zorkoltseva IV, Axenovich TI, Oostra BA, Janssens AC, van Duijn CM.
[MOL PSYCHIATR]
|
|
An R package "VariABEL" for genome-wide searching of potentially interacting loci by testing genotypic variance heterogeneity
Struchalin MV, Amin N, Eilers PH, Duijn CM, Aulchenko YS
[BMC GENET]
|
|
Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations
Demirkan A, van Duijn CM, Ugocsai P, Isaacs A, Pramstaller PP, Liebisch G, Wilson JF, Johansson Å, Rudan I, Aulchenko YS, Kirichenko AV, Janssens AC, Jansen RC, Gnewuch C, Domingues FS, Pattaro C, Wild SH, Jonasson I, Polasek O, Zorkoltseva IV, Hofman A, Karssen LC, Struchalin M, Floyd J, Igl W, Biloglav Z, Broer L, Pfeufer A, Pichler I, Campbell S, Zaboli G, Kolcic I, Rivadeneira F, Huffman J, Hastie ND, Uitterlinden A, Franke L, Franklin CS, Vitart V; DIAGRAM Consortium, Nelson CP, Preuss M; CARDIoGRAM Consortium, Bis JC, O'Donnell CJ, Franceschini N; CHARGE Consortium, Witteman JC, Axenovich T, Oostra BA, Meitinger T, Hicks AA, Hayward C, Wright AF, Gyllensten U, Campbell H, Schmitz G; EUROSPAN consortium
[PLOS GENET]
|
|
Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Aβ-40 levels to presenilin 2
Ibrahim-Verbaas CA, Zorkoltseva IV, Amin N, Schuur M, Coppus AM, Isaacs A, Aulchenko YS, Breteler MM, Ikram MA, Axenovich TI, Verbeek MM, van Swieten JC, Oostra BA, van Duijn CM.
[HUM GENET]
|
|
Rapid variance components-based method for whole-genome association analysis
Svishcheva GR, Axenovich TI, Belonogova NM, van Duijn CM, Aulchenko YS.
[NAT GENET]
|
|
The Empirical Power of Rare Variant Association Methods: Results from Sanger Sequencing in 1,998 Individuals
Ladouceur M, Dastani Z, Aulchenko YS, Greenwood CMT, Richards JB
[PLOS GENET]
|
| 2011 |
Linkage and association analyses of glaucoma related traits in a large pedigree from a Dutch genetically isolated population
Axenovich T, Zorkoltseva I, Belonogova N, van Koolwijk L, Borodin P, Kirichenko A, Babenko V, Ramdas W, Amin N, Despriet D, Vingerling J, Lemij H, Oostra BA, Klaver C, Aulchenko Y, van Duijn C.
[J MED GENET]
|
| 2010 |
A Genome-Wide Screen for Depression in Two Independent Dutch Populations
Schol-Gelok S, Janssens AC, Tiemeier H, Liu F, Lopez-Leon S, Zorkoltseva IV, Axenovich TI, van Swieten JC, Uitterlinden AG, Hofman A, Aulchenko YS, Oostra BA, van Duijn CM.
[BIOL PSYCHIAT]
|
|
A powerful genome-wide feasible approach to detect parent-of-origin effects in studies of quantitative traits
Belonogova NM, Axenovich TI, Aulchenko YS
[EUR J HUM GENET]
|
|
Association between Type 2 Diabetes Loci and Measures of Fatness
Pecioska S, Zillikens MC, Henneman P, Snijders PJ, Oostra BA, van Duijn CM, Aulchenko YS
[PloS One]
|
|
Genetic Architecture of Plasma Adiponectin Overlaps With the Genetics of Metabolic Syndrome-Related Traits
Henneman P, Aulchenko YS, Frants RR, Zorkoltseva IV, Zillikens MC, Frolich M, Oostra BA, van Dijk KW, van Duijn CM.
[DIABETES CARE]
|
|
Linkage and Genome-wide Association Analysis of Obesity-related Phenotypes: Association of Weight With the MGAT1 Gene OBESITY
Johansson A, Marroni F, Hayward C, Franklin CS, Kirichenko AV, Jonasson I, Hicks AA, Vitart V, Isaacs A, Axenovich T, Campbell S, Floyd J, Hastie N, Knott S, Lauc G, Pichler I, Rotim K, Wild SH, Zorkoltseva IV, Wilson JF, Rudan I, Campbell H, Pattaro C, P
[OBESITY]
|
|
MQScore_SNP software for multipoint parametric linkage analysis of quantitative traits in large pedigrees
Axenovich TI, Aulchenko YS.
[ANN HUM GENET]
|
|
ParallABEL: an R library for generalized parallelization of genome-wide association studies
Sangket U, Mahasirimongkol S, Chantratita W, Tandayya P, Aulchenko YS.
[BMC BIOINFORMATICS]
|
|
Ped_Outlier software for automatic identification of within-family outliers
Zorkoltseva IV, Aulchenko YS, van Duijn CM, Axenovich TI.
[COMPUT BIOL CHEM]
|
|
ProbABEL package for genome-wide association analysis of imputed data
Aulchenko YS, Struchalin MV, van Duijn CM.
[BMC BIOINFORMATICS]
|
|
The apolipoprotein E gene and its age-specific effects on cognitive function
Liu F, Pardo LM, Schuur M, Sanchez-Juan P, Isaacs A, Sleegers K, de Koning I, Zorkoltseva IV, Axenovich TI, Witteman JC, Janssens AC, van Swieten JC, Aulchenko YS, Oostra BA, van Duijn CM.
[NEUROBIOL AGING]
|
|
Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations
Struchalin MV, Dehghan A, Witteman JC, van Duijn C, Aulchenko YS.
[BMC GENET]
|
| 2009 |
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation
Estrada K, Krawczak M, Schreiber S, van Duijn K, Stolk L, van Meurs JB, Liu F, Penninx BW, Smit JH, Vogelzangs N, Hottenga JJ, Willemsen G, de Geus EJ, Lorentzon M, von Eller-Eberstein H, Lips P, Schoor N, Pop V, de Keijzer J, Hofman A, Aulchenko YS, Oost
[HUM MOL GENET]
|
|
Association of FGFR2 gene polymorphisms with the risk of breast cancer in population of West Siberia
Boyarskikh UA, Zarubina NA, Biltueva JA, Sinkina TV, Voronina EN, Lazarev AF, Petrova VD, Aulchenko YS, Filipenko ML
[EUR J HUM GENET]
|
|
Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis
Johansson A, Marroni F, Hayward C, Franklin CS, Kirichenko AV, Jonasson I, Hicks AA, Vitart V, Isaacs A, Axenovich T, Campbell S, Dunlop MG, Floyd J, Hastie N, Hofman A, Knott S, Kolcic I, Pichler I, Polasek O, Rivadeneira F, Tenesa A, Uitterlinden AG, Wi
[HUM MOL GENET]
|
|
Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations
Hicks AA, Pramstaller PP, Johansson A, Vitart V, Rudan I, Ugocsai P, Aulchenko Y, Franklin CS, Liebisch G, Erdmann J, Jonasson I, Zorkoltseva IV, Pattaro C, Hayward C, Isaacs A, Hengstenberg C, Campbell S, Gnewuch C, Janssens AC, Kirichenko AV, König
[PLOS GENET]
|
|
Linkage analysis of adult height in a large pedigree from a Dutch genetically isolated population
Axenovich T.I., Zorkoltseva I.V., Belonogova N.M. Struchalin, MV; Kirichenko, AV); Kayser, M); Oostra, BA; van Duijn, CM; Aulchenko, YS .
[HUM GENET]
|
|
PedStr Software for Cutting Large Pedigrees for Haplotyping, IBD Computation and Multipoint Linkage Analysis
Kirichenko A.V., Belonogova N.M., Aulchenko Y.S., Axenovich, TI
[ANN HUM GENET]
|
|
Predicting human height by Victorian and post-genomic methods
Aulchenko Y.S., Struchalin M.V., Belonogova N.M. Axenovich, TI; Weedon, MN; Hofman, A; Uitterlinden, AG; Kayser, M; Oostra, BA; van Duijn, CM; Janssens, ACJW; Borodin, PM.
[ANN HUM GENET]
|
| 2008 |
An approach for cutting large and complex pedigrees for linkage analysis
Liu F, Kirichenko A, Axenovich TI, et al.
[EUR J HUM GENET]
|
|
Breaking loops in large complex pedigrees
Axenovich TI, Zorkoltseva IV, Liu F, Kirichenko AV, Aulchenko YS
[HUM HERED]
|
| 2007 |
A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population
Liu F, Arias-Vásquez A, Sleegers K, Aulchenko YS, Kayser M, Sanchez-Juan P, Feng BJ, Bertoli-Avella AM, van Swieten J, Axenovich TI, Heutink P, van Broeckhoven C, Oostra BA, van Duijn CM
[AM J HUM GENET]
|
|
Genomewide rapid association using mixed model and regression: A fast and simple method for genomewide pedigree-based quantitative trait loci association analysis
Aulchenko YS, de Koning DJ, Haley C
[GENETICS]
|
|
Heritability of blood pressure traits and the genetic contribution to blood pressure variance explained by four blood-pressure-related genes
van Rijn MJ, Schut AF, Aulchenko YS, Deinum J, Sayed-Tabatabaei FA, Yazdanpanah M, Isaacs A, Axenovich TI, Zorkoltseva IV, Zillikens MC, Pols HA, Witteman JC, Oostra BA, van Duijn CM
[J HYPERTENS]
|
| 2006 |
Chromosome-wise dissection of the genome of the extremely big mouse
Bevova MR, Aulchenko YS, Aksu S, Renne U, Brockmann GA.
[GENETICS]
|
|
Heritability of fasting glucose levels in a young genetically isolated population
Santos RL, Zillikens MC, Rivadeneira FR, Pols HA, Oostra BA, van Duijn CM, Aulchenko YS.
[DIABETOLOGIA]
|
|
Ignoring distant genealogic loops leads to false-positives in homozygosity mapping
Liu F., Elefante S., van Duijn CM., Aulchenko YS
[ANN HUM GENET]
|
|
Solution for underflow problem in linkage and segregation analysis
Axenovich T.I., Aulchenko Y.S.
[COMPUT BIOL CHEM]
|
|
Методологические подходы и стратегии картирования генов, контролирующих комплексные признаки человека
Аульченко Ю.С., Аксенович Т.И.
[Информационный вестник ВОГИС]
|
Монографии
| 2021 |
Практическая молекулярная генетика для начинающих: 8–9-е классы.
Аульченко Ю.С., Баттулин Н.Р., Бородин П.М., Воронина Е.Н., Карташов М.Ю., Колесникова Т.Д., Нижников А.А., Пилипенко А.С., Посух О.В., Седых С.Е., Соловьев В.И., Торгашева Н.А., Фишман В.С., Хлесткина Е.К., Цыбко А.С., Шнайдер Т.А., Юнусова А.М.
|
| 2010 |
Effects of Population Structure in Genome-wide Association Studies
Yurii Aulchenko
|
Конференции
| 2023 |
Bidirectional Mendelian randomization analysis of back pain and 22 associated factors
Elgaeva EE, Williams FMK, Zaytseva OO, Freidin MB, Aulchenko YS, Tsepilov YA, Suri P
[European Human Genetics Conference, Hybrid Conference]
|
|
Repurposing antihypertensive and statin medications for spinal pain: a Mendelian randomization study
Suri P, Elgaeva EE, Williams FMK, Freidin MB, Aulchenko YS, Tsepilov YA
[18th International Forum for Back and Neck Pain Research in Primary Care]
|
| 2022 |
Defining the genetic control of N-glycosylation human blood plasma proteins using multivariate genetic association analysis
TIMOSHCHUK A., POTAPOVA N.A., AKMACIC I.T., LAUC G., SHARAPOV S., AULCHENKO Y.S.
[Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022)]
|
|
Association of PANX3 with chronic back pain discovered using gene-based analysis.
Belonogova N.M., Kirichenko A.V., Freidin M.B., Williams F. M. K., Suri P., Aulchenko Y. S., Axenovich T. I., Tsepilov Y. A.
[BGRS/SB-2022 The Thirteenth International Multiconference]
|
|
Association between polygenic risk scores for plasma protein N-glycosylation traits and 276 ICD-10 diseases
ZAYTSEVA O.O., NOSTAEVA A.V., SHARAPOV S.ZH., ELGAEVA E.E., LAUC G., AULCHENKO Y.S., TSEPILOV Y.A.
[Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) : The Thirteenth International Multiconference]
|
|
Bidirectional Mendelian randomization study reveals causal effects of psychosocial factors on chronic back pain and vice versa
ELGAEVA E., WILLIAMS F., FREIDIN M., ZAYTSEVA O., AULCHENKO Y., TSEPILOV Y., SURI P.
[Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) : The Thirteenth International Multiconference]
|
|
Genetic components of chronic back pain may underpin distinct subtypes of the disease
Elgaeva E, Freidin M, Williams F, Suri P, Aulchenko YS, Tsepilov Y
[European Society of Human Genetics Conference ESHG 2022]
|
|
The influence of environmental and genetic factors on the portability of polygenic risk score models across diverse ancestry groups
NOSTAEVA A., KUZNETSOV I., ZHAIVORON A., AULCHENKO Y., KARSSEN L.
[Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) : The Thirteenth International Multiconference]
|
| 2021 |
Insights into the genetic components of chronic back pain
Elizaveta E. Elgaeva, Maxim B. Freidin, Frances M. K. Williams, Pradeep Suri, Yurii S. Aulchenko, Yakov A. Tsepilov
[10th Moscow Conference on Computational Molecular Biology МССМВ21]
|
|
Quantitative genetics of human protein N-glycosylation
Yurii Aulchenko
[10th Moscow Conference on Computational Molecular Biology МССМВ21]
|
|
Analysis of the genetic components behind the chronic back pain
Elizaveta E. Elgaeva, Maxim B. Freidin, Frances M. K. Williams, Pradeep Suri, Yurii S. Aulchenko, Yakov A. Tsepilov
[ASHG Virtual Meeting 2021]
|
|
Mapping genes involved in control of N-glycosylation of blood glycoproteins through a large genome-wide association study.
Sharapov S., Tsepilov Y., Elgaeva E., Tiys E., Nostaeva A., Vuckovic F., Trbojević-Akmačič I., Georges M., Suhre K., Chaturvedi N., Campbell H., Dunlop M., Williams F., Schulze M., Spector T., Lauc G., Aulchenko Y.
[МССМВ'21. 10th Moscow Conference on Computational Molecular Biology]
|
|
Meta-analysis of genome-wide association studies for N-glycosylation in 10,000 individuals.
Sodbo Sharapov, Yakov Tsepilov, Elizaveta Elgaeva, Evgeny Tiys, Arina Nostaeva, Frano Vuckovic, Irena Trbojević-Akmačić, Michel Georges, Karsten Suhre, Nishi Chaturvedi, Harry Campbell, Malcolm Dunlop, Frances Williams, Matthias B. Schulze, Tim Spector, Gordan Lauc, Yurii S. Aulchenko.
[European Human Genetics Conference 2021 (ESHG 2021)]
|
|
Omingenic model of control of N-glycosylation of immunoglobulin G
Arina Nostaeva, Sodbo Sharapov, Gordan Lauc, Michel Georges, Yury Aulchenko
[European Conference of Human Genetics]
|
|
Omingenic model through a lens of genetics of protein N-glycosylation
Aulchenko Yurii, Kuznetsov Ivan, Nostaeva Arina, Lauc Gordan, Georges Michel
[Biology of Genomes]
|
| 2020 |
Loci and genes involved in chronic musculoskeletal pain identified via analysis of genetically independent pain phenotypes
Y Tsepilov, M Freidin, A Shadrina, E Elgaeva, S Sharapov, J van Zunder, L Karssen, P Suri, F Williams, Y Aulchenko
[BGRS/SB-2020: 12th International Multiconference “Bioinformatics of Genome Regulation and Structure/Systems Biology”]
|
|
Novel loci associated with plasma immunoglobulin G N-glycosylation identified by a multivariate analysis
Alexandra S. Shadrina, Alexander S. Zlobin, Olga O. Zaytseva, Gordan Lauc, Lucija Klaric, Sodbo Z. Sharapov, Yurii S. Aulchenko, Yakov A. Tsepilov
[BGRS/SB-2020: 12th International Multiconference “Bioinformatics of Genome Regulation and Structure/Systems Biology”]
|
|
Loci and Genes Involved in Chronic Musculoskeletal Pain Identified via Analysis of Genetically Orthogonal Pain Phenotypes
Y Tsepilov, M Freidin, A Shadrina, E Elgaeva, S Sharapov, J van Zunder, L Karssen, P Suri, F Williams, Y Aulchenko
[European Mathematical Genetics Meeting]
|
|
Quantitative genetics and computational functional genomics as tools to study biology
Aulchenko Y.S.
[BGRS/SB-2020: 12th International Multiconference “Bioinformatics of Genome Regulation and Structure/Systems Biology”]
|
|
Results of genome-wide association study of plasma proteome
N-glycosylation in 10,000 samples
Sodbo Sharapov, Yurii Aulchenko, Tim Spector, Sofya Feoktistova, Yakov A. Tsepilov, Elizaveta E. Elgaeva, Lucija Klaric, Eugene Tiys, Frano Vuckovic, Harry Campbell, Karsten Suhre, Matthias Schulze, Malcolm Dunlop, Frances Williams, Gordan Lauc
[BGRS/SB-2020: 12th International Multiconference “Bioinformatics of Genome Regulation and Structure/Systems Biology”]
|
| 2019 |
Insight into the genetic architecture of back pain and its risk factors from a large genome-wide association study
Цепилов Я.А., Аульченко Ю.С.
[MCCMB 2019]
|
|
Genetic control of human blood plasma N-glycome
Sharapov S. Z.,Tsepilov Y.A. , Lauc G., Aulchenko Y.S.
[VI Съезд биохимиков России]
|
|
Genetic differences determining inter-individual variation in protein glycosylation
Аульченко Ю.С., Шарапов С.Ж.
[11th ISABS and 2nd Human Glycome Meeting]
|
|
Genetic landscape of human healthspan
Zenin A, Tsepilov Y, Sharapov S, Getmantsev E, Menshikov LI, Fedichev PO, Aulchenko Y
[9th Moscow Conference on Computational Molecular Biology МССМВ'19]
|
|
Genetic loci, associated with glycosylation of human total plasma proteins: a 2019 update
Sodbo Zh Sharapov, Yakov A Tsepilov, Lucija Klaric, Massimo Mangino, Gaurav Thareja, Alexandra S Shadrina, Mirna Simurina, Concetta Dagostino, Julia Dmitrieva, Marija Vilaj, Frano Vuckovic, Tamara Pavic8, Jerko Stambuk, Irena Trbojevic-Akmacic, Jasminka Kristic, Jelena Simunovic, Ana Momcilovic, Harry Campbell, Margaret Doherty, Malcolm G Dunlop, Susan M Farrington, Maja Pucic-Bakovic, Christian Gieger, Massimo Allegri, Edouard Louis, Michel Georges, Karsten Suhre, Tim Spector, Frances MK Williams, Gordan Lauc, Yurii S Aulchenko
[11th ISABS Conference on Forensic and Anthropologic Genetics]
|
|
LARGE GENOME-WIDE ASSOCIATION STUDY PROVIDES INSIGHT INTO THE GENETIC ARCHITECTURE OF LOW BACK PAIN AND ITS RISK FACTORS
Tsepilov Y.A., Ю.С. Аульченко
[47th European Mathematical Genetics Meeting]
|
| 2018 |
Defining the genetic control of human blood plasma glycome
using genome-wide association study
S. Sharapov, Y. Tsepilov, L. Klaric, M. Mangino, F. Vuckovic, H. Csmpbell, M. Dunlop, S. Farrington, K. Suhre, T. Spector, G. Lauc, Y. Aulchenko
[SibBioMed]
|
|
GWAS -MAP: a platform for storage and analysis of the results
of thousands of genome-wide association scans
D.D. Gorev, T.I. Shashkova, E. Pakhomov, A. Torgasheva, L. Klaric, A. Severinov, S. Sharapov, D.G. Alexeev, Y.S. Aulchenko
[BGRS]
|
|
Genetic regulation of immunoglobulin G N-glycosylation
L. Klaric, Y. Tsepilov, M. Mangino, T. Esko, P. Salo, S.J. McGurnaghan, F. Vuckovic, H.M. Colhoun, M. Dunlop,
M. Perola, K. Fischer, O. Polasek, J. Wilson, T. Spector, Y.S. Aulchenko, C. Hayward, G. Lauc
[BGRS\SB-2018]
|
|
LARGE GENOME-WIDE ASSOCIATION STUDY PROVIDES INSIGHT INTO THE GENETIC ARCHITECTURE OF LOW BACK PAIN AND ITS RISK FACTORS
Yakov A Tsepilov, Maxim B Freidin, Melody Palmer, Lennart C Karssen, Pradeep Suri, Yurii S Aulchenko, Frances MK Williams
[BGRS\SB-2018 The 11th International Conference Systems Biology and Biomedicine, SBioMed-2018 Symposium]
|
|
Mining large database of genome-wide associations to identify
biomarkers and intervention targets
T.I. Shashkova, A. Torgasheva, D.D. Gorev, E. Pakhomov, L. Klaric, A.V. Severinov, S. Sharapov, Y.A. Tsepilov, D.G. Alexeev, J.F. Wilson, P. Joshi, Y.S. Aulchenko
[BGRS]
|
|
Understanding the genetic control of human blood plasma glycome using genome-wide association study
S. Sharapov, Y. Tsepilov, L. Klaric, M. Mangino, F. Vuckovic, H. Csmpbell, M. Dunlop, S. Farrington, K. Suhre, Gaurav Thareja, T. Spector, G. Lauc, Y. Aulchenko
[GlycoCom 2018]
|
| 2017 |
Progress and perspectives in understanding genetic control of complex human traits
Аульченко Юрий Сергеевич
[8th Moscow Conference on Computational Molecular Biology (MCCMB'17)]
|
|
Количественная генетика: история и перспективы
Аульченко Юрий Сергеевич
[Летняя школа по биоинформатике, Институт биоинформатики]
|
| 2016 |
Imputation and meta-analysis of GWAS results for metabolites measured by different platforms
Tsepilov Y.A., Molnos S., Kastenmüller G., Grallert H., Aulchenko Y.S., Gieger C.
[Understanding the Function of Human Genome Variation, 2016 Keystone Symposia]
|
|
ADDITIVITY AND NON-ADDITIVITY OF GENETIC CONTROL OF HUMAN METABOLOME
Tsepilov Y.A., Shin S., Soranzo N., Spector TD., Adamski J., Kastenmüller G., Strauch K., Wang-Sattler R.,Gieger C., Aulchenko Y.S., Ried J.S.
[BGRS 2016]
|
|
Genome-wide association studies of complex human traits: history and perspectives
Y.S.Aulchenko
[BGRS\SB-2016, SBioMed-2016 and Structure\ Systems Biology — BGRS\SB-2016 Symposium Systems Biology and Biomedicine (SBioMed-2016)]
|
|
Genome-wide association studies of omics data
Цепилов Я.А., Аульченко Ю.С.
[V Съезд биохимиков России]
|
|
Multivariate analysis substantially increases power of genome-wide association analysis of human IgG N-glycosylation
Xia Shen, Lucija Klarić, Massimo Mangino, Irena Trbojević-Akmačić, Maja Pučić-Baković, Igor Rudan, Ozren Polašek, Caroline Hayward, Tim Spector, James Wilson, Gordan Lauc, Yurii Aulchenko
[Understanding the Function of Human Genome Variation]
|
| 2015 |
Сovariate-selection approach in Genome Wide Association Studies for multivariate data
Tsepilov Y.A., Kastenmüller G., Wang-Sattler R., Strauch K.,Gieger C., Aulchenko Y.S.
[American Society of Human Genetics]
|
| 2014 |
When genomics meets other omics: the potential of multi-omics for disentangling human diseases
Аульченко Юрий Сергеевич
["Post-Genome Methods of Analysis in Biology and Laboratory and Clinical Medicine"]
|
|
“Training for and through research in statistical omics: experience of RSSSO2014”
Аульченко Юрий Сергеевич
[«Bertinoro Computational Biology 2014»]
|
|
Genetic interactions in control of human metabolome: a genome-wide variance heterogeneity analysis.
Sodbo Sharapov, Yurii Aulchenko
[Bertinoro Computational Biology 2014]
|
|
Genome-wide environmental sensitivity analysis of human metabolomics data
Sharapov S. Zh., Tsepilov Y.A., Ried J.S., Strauch K., Gieger C., Aulchenko Y.S.*
[Bioinformatics of Genome Regulation and Structure\Systems Biology — BGRS\SB-2014]
|
|
"Omics: Genomics Meets Glycomics in Translational Medicine"
Аульченко Юрий Сергеевич
[Международный симпозиум по клинической и трансляционной медицине"]
|
|
Поиск статистических взаимодействий на данных по метаболому плазмы крови человека.
ШАРАПОВ С. Ж., ЦЕПИЛОВ Я. А., РИЕД Я. С., СТРАУХ К., ГИГЕР К., АУЛЬЧЕНКО Ю.С.
[Международная научная студенческая конференция]
|
|
Genome-wide environmental sensitivity analysis of human metabolomics data.
Sharapov S. Zh., Tsepilov Y.A., Ried J.S., Strauch K., Gieger C., Aulchenko Y.S.
[European Mathematical Genetics Meeting 2014]
|
| 2013 |
Computational aspects of non-additive effects analysis of genes in human metabolomics
Tsepilov Y.A. Ried J.S Gieger C. Strauch K. Shin S. Soranzo N. Spector T. Aulchenko Y.S.
[Aachen Conference on Computational Engineering Science]
|
|
Computational challenges in statistical genomics - a biologist's perspective
Aulchenko YS
[Aachen Conference on Computational Engineering Science]
|
|
Fast mixed models for whole-genome association studies
Aulchenko YS
[European Mathematical Genetics Meeting]
|
|
GENOMIC CONTROL FOR GENOME-WIDE ASSOCIATION ANALYSIS UNDER NON-ADDITIVE MODELS
Tsepilov Y.A. Read J.S. Strauch K. Cornelia M. van Duijn Axenovich T.I. Aulchenko Y.S.
[European Mathematical Genetics Meeting 2013]
|
|
Genomewide linkage scan for principal components of phospho- and sphingolipids level in blood
I. Zorkoltseva, N. Belonogova, A. Demirkan, N. Amin, A. Kirichenko, Y. Aulchenko, C. M. van Duijn2, T. Axenovich
[Annual meeting of European Society of Human Genetics, Paris, France, 8-11 June, 2013.]
|
|
Identification of gene-gene interactions in genome-wide association analysis.
Sharapov S. Zh., Tsepilov Y.A., Ried J.S, Strauch K., Gieger C., Aulchenko Y.S.
[The Aachen Conference on Computational Engineering Science 2013]
|
|
Methods and tools for fast efficient mixed-models based whole-genome association analysis for large cohorts and multiple phenotypes
Aulchenko YS
[American Society of Human Genetics]
|
|
Non-additive effects of genes in human metabolomics
Tsepilov Y.A. Ried J.S. Gieger C. Strauch K. Shin S. Soranzo N. Spector T.I. Aulchenko Y.S.
[American Society of Human Genetics]
|
|
Region-based association analysis of human quantitative traits in related individuals
Белоногова Надежда Михайловна, Свищева Гульнара Рустамовна, Аульченко Юрий Сергеевич, Аксенович Татьяна Иосифовна
[European Conference of Human Genetics, France 2013]
|
|
The GenABEL suite for genome-wide association analyses
Aulchenko YS
[UseR!]
|
| 2012 |
DEVELOPMENT AND APPLICATION OF THE GENOMIC CONTROL METHODS FOR GENOME-WIDE ASSOCIATION ANALYSIS USING NON-ADDITIVE MODELS
Tsepilov Y.A. Read J.S. Strauch K. Axenovich T.I. Aulchenko Y.S.
[BGRS]
|
|
STATISTICAL AND COMPUTATIONAL METHODS FOR GENETIC ANALYSIS OF COMPLEX HUMAN TRAITS
Aulchenko YS
[Postgenomic methods of analysis in biology, and laboratory and clinical medicine]
|
| 2011 |
Genome-wide linkage and association analyses in nondemented hypertensive individuals suggest association of PSEN2 with plasma amyloid beta.
Ibrahim-Verbaas CA, Zorkoltseva IV, Amin N, Schuur M, Aulchenko YS, Breteler MMB, Van der Lugt A, Ikram MA, Axenovich TI, Verbeek MM, Van Swieten JC, Oostra BA, Van Duijn CM.
[Annual meeting of European Society of Human Genetics, Amsterdam, the Netherlands, 25-28 May, 2011.]
|
|
New Developments in Statistical GWAS Methodology in Human Populations
Yurii Aulchenko
[LUPA workshop]
|
| 2010 |
A genome-wide linkage scan of personality traits reveals new loci.
Amin N, Janssens ACJW, Zorkoltseva IV, Axenovich TI, Aulchenko YS, Oostra BA, van Duijn C M.
[Annual meeting of European Society of Human Genetics, Goteborg, Sweden, 12-15 June, 2010.]
|
|
Challenges in statistical genomics of complex human traits
Yurii Aulchenko
[European Mathematical Genetics Meeting]
|
|
Methods for genome-wide association analyses of quantitative trait loci in human genetically isolated populations
Yurii Aulchenko
[QTL/MAS workshop]
|
| 2009 |
Genome-wide linkage scan of human cognitive abilities in a large Dutch pedigree.
Zorkoltseva IV, Schuur M, Kirichenko A, van Swieten J, de Koning I, Oostra B, Aulchenko Y, Axenovitch T, van Duijn C.
[Annual meeting of European Society of Human Genetics, Vienna, Austria, 23-26 May, 2009.]
|
|
Genome-wide parametric linkage analysis of adult height.
Axenovitch TI, Zorkoltseva IV, Belonogova NM, Kirichenko AV, Oostra BA, van Duijn CM, Aulchenko YS.
[Annual meeting of European Society of Human Genetics, Vienna, Austria, 23-26 May, 2009.]
|
|
Predicting human height by Victorian and post-genomic methods
Yurii S. Aulchenko, Maksim V. Struchalin, Nadezhda M. Belonogova, Tatiana I. Axenovich, Michael N. Weedon, Albert Hofman, Andre G. Uitterlinden, Manfred Kayser, Ben A. Oostra, Cornelia M. van Duijn, A. Cecile J. W. Janssens, Pavel M. Borodin
[European Mathematical Genetics Meeting]
|
|
Statistical and Bioinformatical Challenges in the Analysis of Genome-Wide Association Data
Yurii Aulchenko
[Harmonizing Biobank Research]
|
| 2006 |
A package of programs for quality control of genetic data.
Zorkoltseva I., Axenovich T., Aulchenko Yu., Struchalin M.
[Annual meeting of European Society of Humag Genetics, Amsterdam, the Netherlands, 6-9 May, 2006.]
|
|
Genome-wide screen for late onset Alzheimer’s disease in a complex pedigree from a genetically isolated population
F. Liu, A. Arias-Vбsquez, Y. S. Aulchenko, K. Sleegers, P. Sanchez- Juan, A. M. Bertoli-Avella, B. J. Feng, A. Isaacs, P. Heutink, C. van Broeckhoven, B. A. Oostra, C. M. van Duijn
[38th European Human Genetics Conference, Amsterdam, Holland, May]
|
Гранты
| 2019 |
Гены - регуляторы гликозилирования белков человека
Аульченко Юрий Сергеевич
Шарапов Содбо Жамбалович
Торгашева Анна Александровна
Шадрина Александра Сергеевна
Елгаева Елизавета Евгеньевна
Белоногова Надежда Михайловна
Кириченко Анатолий Владимирович
Пахомов Евгений Дмитриевич
Шашкова Татьяна Игоревна
|
| 2015 |
Разработка методов многомерного мета-анализа биологических данных
Аульченко Юрий Сергеевич Шарапов Содбо Жамбалович Цепилов Яков Александрович Белоногова Надежда Михайловна Свищёва Гульнара Рустамовна Злобин Александр Сергеевич Грищенко Александр Константинович
|
|
Разработка теоретических методов оценки предиктивного потенциала полигенных профилей риска мультифакториальных заболеваний
Аульченко Юрий Сергеевич Цепилов Яков Александрович Шарапов Содбо Жамбалович Слепухина Анастасия Александровна Кох Наталья Викторовна
|
| 2014 |
Международный грант для создания лаборатории «Теоретической и прикладной функциональной геномики».
Зайцева Ольга Олеговна, Цепилов Яков Александрович, Шарапов Содбо Жамбалович, Аульченко Наталия Владимировна, Злобин Александр Сергеевич, Грищенко Александр Константинович, Быкова Ирина Вениаминовна, Курильщиков Александр Михайлович, Алексеев Дмитрий Глебович, Пахомов Евгений Дмитриевич, Юзаю Ксения Александровна
|
|
Разработка методов полногеномного анализа данных функциональной геномики
Аксенович Татьяна Иосифовна, Цепилов Яков Александрович, Шарапов Содбо Жамбалович, Зайцева Ольга Олеговна, Аульченко Наталия Владимировна, Белоногова Надежда Михайловна, Злобин Александр Сергеевич, Грищенко Александр Константинович, Быкова Ирина Вениаминовна
|
| 2012 |
Роль генетических взаимодействий в контроле метаболома человека
Аульченко Юрий Сергеевич, Свищёва Гульнара Рустамовна, Цепилов Яков Александрович, Christian Gieger, Janina S. Ried, Konstantin Strauch
|
|
Разработка и применение методов полногеномного анализа высокоразмерных признаков с помощью смешанных моделей
Аульченко Юрий Сергеевич, Белоногова Надежда Михайловна, Свищёва Гульнара Рустамовна, Цепилов Яков Александрович, Шарапов Содбо Жамбалович
|
| 2011 |
Поиск генов, контролирующих уровень фосфо- и сфинголипидов в плазме крови
Аксенович Татьяна Иосифовна, Аульченко Юрий Сергеевич, Белоногова Надежда Михайловна, Зоркольцева Ирина Витальевна, Кириченко Анатолий Владимирович, Свищева Гульнара Рустамовна
|
| 2007 |
Анализ генетической природы болезни Альцгеймера и когнитивных функций
Аксенович Татьяна Иосифовна, Белоногова Надежда Михайловна, Бородин Павел Михайлович, Зоркольцева Ирина Витальевна, Кириченко Анатолий Владимирович, Аульченко Юрий Сергеевич
|
|
Генетико-статистические аспекты картирования количественных признаков человека и животных
Аульченко Юрий Сергеевич, Зоркольцева Ирина Витальевна, Кириченко Анатолий Владимирович, Свищева Гульнара Рустамовна, Стручалин Максим Владимирович
|
| 2004 |
Изменение генетической структуры сложных признаков млекопитающих в ходе отбора
Аксенович Татьяна Иосифовна, Акбердин Илья Ринатович, Аульченко Юрий Сергеевич, Данильченко Наталья Викторовна, Зоркольцева Ирина Витальевна, Зыкович Артем Сергеевич, Кириченко Анатолий Владимирович, Никитин Сергей Вячеславович, Степика Анна Владимировна
|
Научное руководство
| 2022 |
Полногеномное исследование
ассоциаций уровней N-гликозилирования белков плазмы крови человека
[Шарапов Содбо Жамбалович]
|
| 2021 |
Разработка on-line системы хранения и анализа результатов полногеномных исследований ассоциаций
[Горев Денис Дмитриевич]
|
| 2020 |
Платформа для комплексного анализа результатов полногеномных исследований ассоциаций
[Шашкова Татьяна Игоревна]
|
| 2018 |
Защита диплома аспиранта:
"Исследование генетического контроля гликозилирования белков плазмы крови
человека"
[Шарапов Содбо Жамбалович]
|
| 2017 |
«Разработка и применение новой статистической многомерной модели в анализе комплексных признаков человека»
[Грищенко Александр Константинович]
|
|
Условный и совместный анализ ассоциаций с несколькими признаками на суммарных статистиках мета-анализа
Аульченко Ю.С., Цепилов Я.А., Свищева Г.Р.
[Грищенко Александр Константинович]
|
| 2016 |
Разработка и применение новых моделей в полногеномном анализе ассоциаций
[Цепилов Яков Александрович]
|
| 2015 |
Биоинформатический анализ экзомов представителей якутского этноса
[Злобин Александр Сергеевич]
|
| 2014 |
Поиск ген-генных взаимодействий на метаболоме крови человека
[Шарапов Содбо Жамбалович]
|
| 2012 |
Метод геномного контроля для произвольных моделей наследования
[Цепилов Яков Александрович]
|
Учебные курсы
| 2022 |
Количественная генетика
|
| 2021 |
Introduction to quantitative genetics
|
| 2020 |
Models and methods of human quantitative genetics
Аульченко Ю.С., Шарапов С.Ж., Ностаева А.В.
|
| 2018 |
From Disease to Genes and Back
Marianna Bevova, Yurii Aulchenko, Michel Georges, Lennart Karssen, Lennart Karssen, Yakov Tsepilov, Sodbo Sharapov, Natalia Aulchenko
|
|
Модели и методы количественной и популяционной генетики
Цепилов Я.А., Шарапов С.Ж., Аульченко Ю.С.
|
| 2017 |
Модели и методы количественной генетики
Аульченко Юрий Сергеевич, Цепилов Яков Александрович, Шарапов Содбо Жамбалович
|
| 2015 |
Essential Human Genomics
Michel Georges, Carole Charlier
|
| 2012 |
Введение в статистическую геномику
|
| 2011 |
Статистическая генетика человека
|
Патенты
| 2021 |
База данных генетических ассоциаций признаков овец (ГАПО)
Аульченко Ю.С., Шашкова Т.И., Цепилов Я.А., Кириченко А.В., Злобин А.С.
|
Диссертации
| 2011 |
Разработка и применение методов полногеномного анализа генетических ассоциаций сложных признаков
[Доктор]
|
| 2000 |
Развитие методов сегрегационного анализа: комплексные признаки и сложные родословные
[Кандидат]
|
|
|
