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Елгаева Елизавета Евгеньевна

Подразделение: 132. Межинст. лаб. молек. палеогенет. и палеогеномики
Совместительство: 212. Лаб.разработки статистич.методов оценки наследуемости
190. Лаб.генет.дегенерации межпозвонковых дисков.
Должность: младший научный сотрудник
Комната: 1228
Email: elgaeva@bionet.nsc.ru
Рабочий: +7 (383) 363-49-63*1228


Scopus: http://www.scopus.com/inward/authorDetails.url?authorID=57212082937&partnerID=MN8TOARS



Публикации

2023 Bidirectional Mendelian Randomization Study of Personality Traits Reveals a Positive Feedback Loop Between Neuroticism and Back Pain
Elgaeva EE, Williams FMK, Zaytseva OO, Freidin MB, Aulchenko YS, Suri P, Tsepilov YA
[J PAIN]
Development and Replication of a Genome-Wide Polygenic Risk Score for Chronic Back Pain
Tsepilov YA, Elgaeva EE, Nostaeva AV, Compte R, Kuznetsov I, Karssen LC, Freidin MB, Suri P, Williams FMK, Aulchenko YS
[J. Pers. Med]
Evidence of causal effects of blood pressure on back pain and back pain on type II diabetes provided by a bidirectional Mendelian randomization study
Suri P, Elgaeva EE, Williams FMK, Freidin MB, Zaytseva OO, Aulchenko YS, Tsepilov YA
[SPINE J]
Multi-Trait Exome-Wide Association Study of Back Pain-Related Phenotypes
Zorkoltseva IV Elgaeva EE Belonogova NM Kirichenko AV Svishcheva GR Freidin MB Williams FMK Suri P Tsepilov YA Axenovich TI
[Genes]
Repurposing Antihypertensive and Statin Medications for Spinal Pain: A Mendelian Randomization Study
Suri P, Elgaeva EE, Williams FMK, Freidin MB, Verzun DA, Tsepilov YA
[SPINE]
2022 Causal effects of psychosocial factors on chronic back pain: a bidirectional Mendelian randomisation study
Frances M K Williams, Elizaveta E Elgaeva, Maxim B Freidin, Olga O Zaytseva, Yurii S Aulchenko, Yakov A Tsepilov, Pradeep Suri
[EUR SPINE J]
A novel framework for analysis of the shared genetic background of correlated traits
Gulnara R Svishcheva, Evgeny S Tiys, Elizaveta E Elgaeva, Sofia G Feoktistova, Paul RHJ Timmers, Sodbo Zh Sharapov, Tatiana I Axenovich, Yakov A Tsepilov
[Genes]
A protocol for recruiting and analyzing the disease-oriented Russian disc degeneration study (RuDDS) biobank for functional omics studies of lumbar disc degeneration
Olga N. Leonova, Elizaveta E. Elgaeva, Tatiana S. Golubeva, Alexey V. Peleganchuk, Aleksandr V. Krutko, Yurii S. Aulchenko, Yakov A. Tsepilov
[PloS One]
Mendelian randomization analysis of plasma levels of CD209 and MICB proteins and the risk of varicose veins of lower extremities
Alexandra S Shadrina, Elizaveta E Elgaeva, Ian B Stanaway, Gail P Jarvik, Bahram Namjou, Wei-Qi Wei, Joe Glessner, Hakon Hakonarson, Pradeep Suri, Yakov A Tsepilov
[PloS One]
2020 Candidate genes for age at menarche are associated with endometriosis
Irina Ponomarenko, Evgeny Reshetnikov, Alexey Polonikov, Irina Verzilina, Inna Sorokina, Elizaveta E Elgaeva, Yakov A Tsepilov, Anna Yermachenko, Volodymyr Dvornyk, Mikhail Churnosov
[REPROD BIOMED ONLINE]
Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions
Tsepilov Y. A., Freidin M. B., Shadrina A. S., Sharapov S. Z., Elgaeva E. E., van Zundert J., Karssen L. С., Suri P., Williams F. M. K., Aulchenko Y. S.
[Commun. biolog.]
Replication of 15 loci involved in human plasma protein N-glycosylation in 4,802 samples from four cohorts
Sharapov SZ, Shadrina AS, Tsepilov YA, Elgaeva EE, Tiys ES, Feoktistova SG, Zaytseva OO, Vuckovic F, Cuadrat R, Jäger S, Wittenbecher C, Karssen LC, Timofeeva M, Tillin T, Trbojević-Akmačić I, Štambuk T, Rudman N, Krištić J, Šimunović J, Momčilović A, Vilaj M, Jurić J, Slana A, Gudelj I, Klarić T, Puljak L, Skelin A, Kadić AJ, Van Zundert J, Chaturvedi N, Campbell H, Dunlop M, Farrington SM, Doherty M, Dagostino C, Gieger C, Allegri M, Williams F, Schulze MB, Lauc G, Aulchenko YS.
[GLYCOBIOLOGY]
2019 Examining causal effects of body mass index on back pain: a Mendelian randomization study
Elizaveta E. Elgaeva, Yakov Tsepilov, Maxim B. Freidin, Frances M. K. Williams, Yurii Aulchenko, Pradeep Suri
[EUR SPINE J]

Конференции

2024 The influence of lumbar intervertebral disc degeneration on low back pain is modified by genetic propensity to pain
Suri P, Kazemi-Naeni M, Freidin MB, Tsepilov YA, Elgaeva EE, Granville-Smith I, Compte R, Williams FMK
[The International Society for the Study of the Lumbar Spine Annual meeting]
2023 Bidirectional Mendelian randomization analysis of back pain and 22 associated factors
Elgaeva EE, Williams FMK, Zaytseva OO, Freidin MB, Aulchenko YS, Tsepilov YA, Suri P
[European Human Genetics Conference, Hybrid Conference]
Exome sequencing association analysis replicated the role of rare variants of SLC13A1 in back pain
Zorkoltseva IV, Elgaeva EE, Kirichenko AV, Belonogova NM, Svishcheva GR, Tsepilov YA, Axenovich TI
[European Human Genetics Conference, Hybrid Conference]
Repurposing antihypertensive and statin medications for spinal pain: a Mendelian randomization study
Suri P, Elgaeva EE, Williams FMK, Freidin MB, Aulchenko YS, Tsepilov YA
[18th International Forum for Back and Neck Pain Research in Primary Care]
2022 Association between polygenic risk scores for plasma protein N-glycosylation traits and 276 ICD-10 diseases
ZAYTSEVA O.O., NOSTAEVA A.V., SHARAPOV S.ZH., ELGAEVA E.E., LAUC G., AULCHENKO Y.S., TSEPILOV Y.A.
[Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) : The Thirteenth International Multiconference]
Bidirectional Mendelian randomization study reveals causal effects of psychosocial factors on chronic back pain and vice versa
ELGAEVA E., WILLIAMS F., FREIDIN M., ZAYTSEVA O., AULCHENKO Y., TSEPILOV Y., SURI P.
[Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) : The Thirteenth International Multiconference]
Genetic components of chronic back pain may underpin distinct subtypes of the disease
Elgaeva E, Freidin M, Williams F, Suri P, Aulchenko YS, Tsepilov Y
[European Society of Human Genetics Conference ESHG 2022]
2021 Insights into the genetic components of chronic back pain
Elizaveta E. Elgaeva, Maxim B. Freidin, Frances M. K. Williams, Pradeep Suri, Yurii S. Aulchenko, Yakov A. Tsepilov
[10th Moscow Conference on Computational Molecular Biology МССМВ21]
Shared heredity: a method to model genetic basis of correlated traits
Gulnara R. Svishcheva, Evgeny S. Tiys, Sofia G. Feoktistova, Elizaveta E. Elgaeva, Sodbo Z. Sharapov, Yakov A. Tsepilov
[MCCMB 2021]
Analysis of the genetic components behind the chronic back pain
Elizaveta E. Elgaeva, Maxim B. Freidin, Frances M. K. Williams, Pradeep Suri, Yurii S. Aulchenko, Yakov A. Tsepilov
[ASHG Virtual Meeting 2021]
Evaluation of causal relationships between varicose veins of lower extremities and knee osteoarthritis using large - scale genetic data
Alexandra S. Shadrina, Elizaveta E. Elgaeva, Maxim B. Freidin, Yakov A. Tsepilov
[European Human Genetics Virtual Conference 2021]
Mapping genes involved in control of N-glycosylation of blood glycoproteins through a large genome-wide association study.
Sharapov S., Tsepilov Y., Elgaeva E., Tiys E., Nostaeva A., Vuckovic F., Trbojević-Akmačič I., Georges M., Suhre K., Chaturvedi N., Campbell H., Dunlop M., Williams F., Schulze M., Spector T., Lauc G., Aulchenko Y.
[МССМВ'21. 10th Moscow Conference on Computational Molecular Biology]
Meta-analysis of genome-wide association studies for N-glycosylation in 10,000 individuals.
Sodbo Sharapov, Yakov Tsepilov, Elizaveta Elgaeva, Evgeny Tiys, Arina Nostaeva, Frano Vuckovic, Irena Trbojević-Akmačić, Michel Georges, Karsten Suhre, Nishi Chaturvedi, Harry Campbell, Malcolm Dunlop, Frances Williams, Matthias B. Schulze, Tim Spector, Gordan Lauc, Yurii S. Aulchenko.
[European Human Genetics Conference 2021 (ESHG 2021)]
2020 Association between total plasma N-glycan levels and chronic back pain: a prospective study
Elizaveta E. Elgaeva, Yakov A. Tsepilov, Irena Trbojevic Akmacic, Andrea Skelin, Concetta Dagostino, Massimo Allegri, Jan Van Zundert, Dragan Primorac, Gordan Lauc, Frances M. K. Williams, Maxim B. Freidin
[BGRS/SB-2020: 12th International Multiconference “Bioinformatics of Genome Regulation and Structure/Systems Biology”]
Loci and genes involved in chronic musculoskeletal pain identified via analysis of genetically independent pain phenotypes
Y Tsepilov, M Freidin, A Shadrina, E Elgaeva, S Sharapov, J van Zunder, L Karssen, P Suri, F Williams, Y Aulchenko
[BGRS/SB-2020: 12th International Multiconference “Bioinformatics of Genome Regulation and Structure/Systems Biology”]
Loci and Genes Involved in Chronic Musculoskeletal Pain Identified via Analysis of Genetically Orthogonal Pain Phenotypes
Y Tsepilov, M Freidin, A Shadrina, E Elgaeva, S Sharapov, J van Zunder, L Karssen, P Suri, F Williams, Y Aulchenko
[European Mathematical Genetics Meeting]
A new method for combining of genetically correlated traits by maximizing of their shared heritability
Svishcheva G, Tiys E, Feoktisova S, Elgaeva E, Sharapov S, Tsepilov Y
[48th European Mathematical Genetics Meeting (EMGM)]
Results of genome-wide association study of plasma proteome N-glycosylation in 10,000 samples
Sodbo Sharapov, Yurii Aulchenko, Tim Spector, Sofya Feoktistova, Yakov A. Tsepilov, Elizaveta E. Elgaeva, Lucija Klaric, Eugene Tiys, Frano Vuckovic, Harry Campbell, Karsten Suhre, Matthias Schulze, Malcolm Dunlop, Frances Williams, Gordan Lauc
[BGRS/SB-2020: 12th International Multiconference “Bioinformatics of Genome Regulation and Structure/Systems Biology”]
2019 Genome-wide association study of genetic principal components of four chronic musculoskeletal human pain types
Yakov A. Tsepilov, Maxim B. Freidin, Sodbo Zh. Sharapov, Aleksandra S. Shadrina, Elizaveta E. Elgaeva, Melody Palmer, Lennart C. Karssen, Pradeep Suri, Frances M. K. Williams
[9th Moscow Conference on Computational Molecular Biology МССМВ'19 2019, Москва]
Исследование главных генетических компонент четырех хронических скелетно-мышечных болей человека
Е. Е. Елгаева
[Международная научная студенческая конференция (МНСК-2019)]
2018 Early and late transcriptional responses to the low concentration of salicylic acid in Arabidopsis thaliana L. root
E. Elgaeva, E. Zemlyanskaya, D. Novikova, V. Mironova
[Systems Biology And Bioinformatics (SBB-2018) | The Tenth International Young Scientists School]
Ранний и поздний транскрипционный ответ на низкие концентрации салициловой кислоты в корне Arabidopsis thaliana L.
Е. Е. Елгаева
[Международная научная студенческая конференция]
2016 Виталитетная структура популяций растений в лесных фитоценозах
Елгаева Е. Е.
[Международная научная студенческая конференция]

Гранты

2023 Разработка статистических методов оценки наследуемости, объясняемой редкими генетическими вариантами, и использование этих методов для анализа социально-значимых патологий
Свищёва Гульнара Рустамовна, Зоркольцева Ирина Витальевна, Белоногова Надежда Михайловна, Елгаева Елизавета Евгеньевна

2022 Генетический контроль дегенерации поясничных межпозвонковых дисков
Цепилов Я.А., Елгаева Е.Е., Леонова О.Н., Белоногова Н.М., Аксенович Т.И., Иванов А.А., Бердникова А.А., Вибе Д.С., Пелеганчук А.В, Фрейдин М.Б.

2020 Разработка теоретических и прикладных основ использования больших данных для картирования генов
Шарапов Содбо Жамбалович Свищёва Гульнара Рустамовна Белоногова Надежда Михайловна Кириченко Анатолий Владимирович Елгаева Елизавета Евгеньевна

Разработка теоретических и прикладных основ использования больших данных для картирования генов
Свищева Гульнара Рустамовна (Р) Белоногова Надежда Михайловна Зоркольцева Ирина Витальевна Аксенович Татьяна Иосифовна Кириченко Анатолий Владимирович Елгаева Елизавета Евгеньевна

2019 Гены - регуляторы гликозилирования белков человека
Аульченко Юрий Сергеевич Шарапов Содбо Жамбалович Торгашева Анна Александровна Шадрина Александра Сергеевна Елгаева Елизавета Евгеньевна Белоногова Надежда Михайловна Кириченко Анатолий Владимирович Пахомов Евгений Дмитриевич Шашкова Татьяна Игоревна

Комплексный подход к анализу генетической архитектуры дорсалгии
Цепилов Я.А., Шадрина А.С., Елгаева Е.Е., Торгашева А.А., Шарапов С.Ж.


Научное руководство

2025 Оценка потерянной наследуемости хронической боли в спине, объясняемой редкими вариантами [Бердникова Анна Александровна]
2023 Разработка метода оценки неаддитивной наследуемости признаков на основе анализа суммарных статистик полногеномных анализов ассоциаций [Пак Баяр]
Поиск оптимальной референсной панели для импутации данных генотипирования выборки россиян [Бердникова Анна Александровна]
2022 Оценка потенциала перепрофилирования лекарственных средств для лечения хронической боли в спине при помощи Менделевской Рандомизации [Верзун Дмитрий Андреевич]
Реализация алгоритма клампинга однонуклеотидных полиморфизмов с учётом неравновесия по сцеплению на платформе GWAS-MAP [Трушин Александр Алексеевич]

Учебные курсы

2024 Биометрия
Теория селекции
2023 Биометрия
2022 Биометрия
Цепилов Я.А., Елгаева Е.Е., Шарапов С.Ж.

Количественная генетика
2021 Компьютерная статистическая геномика
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