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Publications
| 2024 |
Characterizing a Lethal CAG-ACE2 Transgenic Mouse Model for SARS-CoV-2 infection with Using Cas9-Enhanced Nanopore Sequencing
Smirnov A, Nurislamov A, Galina Koncevaya G, Serova I, Kabirova E, Chuyko E, Maltceva E, Savoskin M, Zadorozhny D, Svyatchenko VA, Protopopova EV, Taranov OS, Legostaev SS, Loktev VB, Serov O, Battulin N
[TRANSGENIC RES]
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Knockout of the Tnfa Gene Decreases Influenza Virus-Induced Histological Reactions in Laboratory Mice
Savenkova D. A., Gudymo A. S., Korablev A. N., Taranov O. S., Bazovkina D. V., Danilchenko N. V., Perfilyeva O. N., Ivleva E. K., Moiseeva A. A., Bulanovich Y. A., Roshchina E. V., Serova I. A., Battulin N. R., Kulikova E. A., Yudkin D. V.
[INT J MOL SCI]
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Structural variants in the Epb41l4a locus: TAD disruption and Nrep gene misregulation as hypothetical drivers of neurodevelopmental outcomes
Paul Salnikov, Alexey Korablev, Irina Serova, Polina Belokopytova, Aleksandra Yan, Yana Stepanchuk, Savelii Tikhomirov, Veniamin Fishman
[SCI REP-UK]
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TAD border deletion at the Kit locus causes tissue-specific ectopic activation of a neighboring gene.
Kabirova E, Ryzhkova A, Lukyanchikova V, Khabarova A, Korablev A, Shnaider T, Nuriddinov M, Belokopytova P, Smirnov A, Khotskin NV, Kontsevaya G, Serova I, Battulin N.
[NAT COMMUN]
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| 2022 |
Evaluation of the α‑casein (CSN1S1) locus as a potential target for a site‑specifc transgene integration
Смирнов А. В., Концевая Г. В., Шнайдер Т. А., Юнусова А. М., Феофанова Н. А., Герлинская Л. А., Серова И. А., Серов О. Л., Баттулин Н. Р.
[SCI REP-UK]
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The human EF1a promoter does not provide expression of the transgene in mice
Nariman Battulin, Alexey Korablev, Anastasia Ryzhkova, Alexander Smirnov, Evelyn Kabirova, Anna Khabarova, Timofey Lagunov, Irina Serova, Oleg Serov
[TRANSGENIC RES]
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ЭКСПЕРИМЕНТАЛЬНОЕ ИЗУЧЕНИЕ
ПРОТИВООПУХОЛЕВОЙ АКТИВНОСТИ ПРЕПАРАТА
"ПЕФАГТАЛ", АДРЕСОВАННОГО К αvβ3-ИНТЕГРИНАМ
Н.А.Попова, В.П.Николин, В.И.Каледин, И.А.Серова, Е.А.Матюнина, М.А.Бакарев, Е.Л.Лушникова, А.Н.Вологодский
[Бюллетень экспериментальной биологии и медицины]
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| 2021 |
A hypomorphic mutation in the mouse csn1s1 gene generated by CRISPR/Cas9 pronuclear microinjection
A V Smirnov, T А Shnaider, A N Korablev, A M Yunusova, I A Serova, N R Battulin
[Vavilov journal of genetics and breeding]
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Pannexin 1 Transgenic Mice: Human Diseases and Sleep-Wake Function Revision
Nariman Battulin, Vladimir M. Kovalzon, Alexey Korablev, Irina Serova, Oxana O. Kiryukhina, Marta G. Pechkova, Kirill A. Bogotskoy, Olga S. Tarasova, Yuri Panchin
[INT J MOL SCI]
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| 2020 |
DNA barcoding reveals that injected transgenes are predominantly processed by homologous recombination in mouse zygote
Alexander Smirnov, Veniamin Fishman, Anastasia Yunusova, Alexey Korablev, Irina Serova, Boris V Skryabin, Timofey S Rozhdestvensky, Nariman Battulin
[NUCLEIC ACIDS RES]
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On-target CRISPR/Cas9 activity can cause undesigned large deletion in mouse zygotes
Alexey Korablev, Varvara Lukyanchikova, Irina Serova, Nariman Battulin
[INT J MOL SCI]
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| 2019 |
Time origin and structural analysis of the induced CRISPR/cas9 megabase-sized deletions and duplications involving the Cntn6 gene in mice.
Inna E. Pristyazhnyuk, Julia Minina, Alexey Korablev, Irina Serova, Veniamin Fishman, Maria Gridina, Timofey S. Rozhdestvensky, Leonid Gubar, Boris V. Skryabin, and Oleg L. Serov
[SCI REP-UK]
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Происхождение и судьба масштабных хромосомных перестроек, индуцированных технологией CRISPR/Cas9 у мышей: от зигот до соматических клеток
Алексей Николаевич Кораблев, Инна Евгеньевна Пристяжнюк, Юлия Михайловна Минина, Ирина Александровна Серова, Вениамин Семенович Фишман, Мария Михайловна Гридина, Timofey Rozhdestvensky, Leonid Gubar, Boris Skryabin, Олег Леонидович Серов
[Гены и клетки]
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| 2018 |
Unexpected phenotypic effects of a transgene integration causing a knockout of the endogenous Contactin-5 gene in mice
Smirnov A.V., Kontsevaya G.V., Feofanova N.A., Anisimova M.V., Serova I.A., Gerlinskaya L.A., Battulin N.R., Moshkin M.P., Serov O.L.
[TRANSGENIC RES]
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| 2017 |
Generation of megabase-scale deletions, inversions and duplications involving the Contactin-6 gene in mice by CRISPR/Cas9 technology
Korablev AN,Serova IA, Serov OL
[BMC GENET]
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Unexpected phenotypic effects of a transgene integration causing a knockout of the endogenous Contactin-5 gene in mice
Smirnov AV, Kontsevaya GV, Feofanova NA, Anisimova MV, Serova IA, Gerlinskaya LA, Battulin NR, Moshkin MP, Serov OL
[TRANSGENIC RES]
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Генерирование мегабазных делеций, дупликаций и инверсий, включающих ген Cntn6, у мышей: экспериментальные модели нейро-психических нарушений человека, вызванных масштабными хромосомными перестройками
Кораблев АН, Серова ИА, Серов ОЛ
[Гены и клетки]
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Манипуляции с ранними эмбрионами мыши для создания генетически модифицированных животных
А.Н. Кораблев, И.А. Серова, Б.В. Скрябин
[Vavilov journal of genetics and breeding]
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| 2016 |
Морфофизиологические эффекты инсерционного мутагенеза гена контактин 5 (Cntn5) у трансгенных мышей
А. В. Смирнов, Н. А. Феофанова, Г. В. Концевая, М. В. Анисимова, И. И. Ковригин, И. А. Серова, М. П. Мошкин, Л. А. Герлинская, Н. Р. Баттулин
[Vavilov journal of genetics and breeding]
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Практическое руководство по редактированию геномов системой CRISPR/Cas9
Мензоров А.Г., Лукьянчикова В.А., Кораблев А.Н., Серова И.А., Фишман В.С.
[Vavilov journal of genetics and breeding]
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| 2014 |
Reproductive parameters and the use of MOET in transgenic founder goat carrying the human granulocyte colony-stimulating factor (hG-CSF) gene
Moura RR, Souza-Fabjan JMG, Fonseca JF, Melo CHS, Sanchez DJD, Vieira MP, Almeida TM, Serova IA, Serov OL, A.F. Pereira AF, Teixeira DIA, Melo LM, Freitas VJF
[Animal Reproduction]
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| 2013 |
Dynamics of recombinant hG-CSF in transgenic goat: Preliminary study in the founder during hormonally induced lactation
R.R. Moura, E.S. Albuquerque, C.H.S.Melo, A.S. Alcântara-Neto, R.I.T. P. Batista, D.C.S. Nunes-Pinheiro, A.F. Pereira, D.Í.A. Teixeira, L.M. Melo, I.A. Serova, L.E. Andreeva, O.L. Serov,V.J.F. Freitas
[Animal Biotechnology]
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Expression of the human granulocyte–macrophage colony stimulating factor (hGM-CSF) gene under control of the 50-regulatory sequence of the goat alpha-S1-casein gene with and without a MAR element in transgenic mice
I. A. Burkov • I. A. Serova • N. R. Battulin • A. V. Smirnov • I. V. Babkin • L. E. Andreeva • G. A. Dvoryanchikov • O. L. Serov
[TRANSGENIC RES]
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The comparison of two embryo donor breeds for the generation of transgenic goats by DNA pronuclear microinjection
Freitas VJF,E, Serova IA, Andreeva LE, Melo LM, Teixeira DIA, Pereira AF, Moura RR, Lopes-Jr ES, Souza-Fabjan JMG, Batista RITP, Serov OL
[ANIM PROD SCI]
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| 2012 |
A 3,387 bp 5'-flanking sequence of the goat alpha-S1-casein gene provides correct tissue-specific expression of human granulocyte colony-stimulating factor (hG-CSF) in the mammary gland of transgenic mice
Serova IA, Dvoryanchikov GA, Andreeva LE, Burkov IA, Dias LPB, Battulin NR, Smirnov AV, Serov OL
[TRANSGENIC RES]
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The establishment of two transgenic goat lines for mammary gland hG-CSF expression
Freitas VJF, Serova IA, Moura RR, Andreeva LE, Melo L.M., Teixeira DIA, Pereira AF, Lopes-Jr ES, Dias LPB, Nunes-Pinheiro DCS, Sousa FC, Alcântara-Neto AS, Albuquerque ES, Melo CHS, Rodrigues VHV, Batista RITP, Dvoryanchikov GA, Serov OL
[SMALL RUMINANT RES]
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| 2010 |
Persistent neutrophilia in clinically healthful hG-CSF-transgenic goats in Brazil source
Melo L. M.; Rodrigues V. H. V.; Moura R. R.Serova I,Melo L, Freitas V
[TRANSGENIC RES]
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Pronuclear embrio yield in Caninde and Saanen goats for DNA microinjection
Moura E.S.,Lopes-Junior E.S,Teixeira D.I.A.,Serova I.A.,Andreeva L.E.,Freitas V.J.F..
[REPROD DOMEST ANIM]
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| 2009 |
Mosaic expression of LacZ gene reporter controlled by 5`-regulatory sequences alpha-S1-casein gene in transgenic mice
Serova IA, Andreeva EI, Khaidarova NV, Dias LPB, Dvoryanchikov GA, Burkov IA, Baginskaya NV
[Cell and Tissue Biology]
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| 2008 |
The use of real-time ultrasonography embryo donors participating in a transgenesis goat
Teixeira DIA, Lopes JES, Sousa FC, Pineiro ESP, Serova I.A., Andreeva LI, Freitas VJF
[SMALL RUMINANT RES]
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| 2007 |
Production of transgenic goat (Capra hircus) with human Granulocyte Colony Stimulating Factor (hG-CSF) gene in Brazil
Freitas VJ, Serova IA, Andreeva LE, Dvoryanchikov GA, Lopes-Jr ES, Teixeira DI, Dias LP, Avelar SR, Moura RR, Melo LM, Pereira AF, Cajazeiras JB, Andrade ML, Almeida KC, Sousa FC, Carvalho AC, Serov OL
[Annals of the Brazilian Academy of Sciences]
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State of the art in the production of transgenic and cloned goats
Freitas GF, Serova IA, Andreeva LE, Serov OL
[Acta Scientiae Veterinariae]
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