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Publications
| 2024 |
Retinoprotective Effect of SkQ1,
Visomitin Eye Drops, Is Associated with Suppression
of P38 MAPK and ERK1/2 Signaling Pathways Activity
Natalia A. Muraleva, Anna A. Zhdankina, Anzhella Zh. Fursova, and Nataliya G. Kolosova
[BIOCHEMISTRY-MOSCOW+]
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Ретинопротекторный эффект SKQ1 – глазных капель Визомитин – связан с подавлением активности сигнальных путей p38MAПK и ERK1/2
Н.А. Муралёва, А.А. Жданкина, А.Ж. Фурсова, Н.Г. Колосова
[Биохимия]
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| 2023 |
Alteration of the MEK1/2-ERK1/2 Signaling Pathway in the Retina Associated with Age and Development of AMD-Like Retinopathy
Natalia A Muraleva, Nataliya G Kolosova
[BIOCHEMISTRY-MOSCOW+]
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P38 MAPK Signaling in the Retina: Effects of Aging and
Age-Related Macular Degeneration
Natalia A. Muraleva, Nataliya G. Kolosova
[INT J MOL SCI]
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Изменение активности MEK1/2–ERK1/2-сигнального пути в сетчатке крыс с возрастом и при развитии признаков возрастной макулярной дегенерации
Н.А.Муралёва, Н.Г.Колосова
[Биохимия]
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Повышение активности ЕРК1/2 и р38МАПК
сигнальных путей — общий механизм развития
болезни Альцгеймера и возрастной макулярной
дегенерации?
Muraleva N.A.
[Гены и клетки]
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| 2022 |
SkQ1 as a Tool for Controlling Accelerated
Senescence Program: Experiments with OXYS Rats
Nataliya G. Kolosova, Oyuna S. Kozhevnikova, Natalia A. Muraleva, Ekaterina A. Rudnitskaya, Yuliya V. Rumyantseva, Natalia A. Stefanova, Darya V. Telegina, Mikhail A. Tyumentsev, and Anzhella Zh. Fursova
[BIOCHEMISTRY-MOSCOW+]
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SkQ1 как инструмент воздействия на программу преждевременного старения: опыт исследований на крысах OXYS
Н.Г. Колосова, О.С. Кожевникова, Н.А. Муралёва, Е.А. Рудницкая, Ю.В. Румянцева, Н.А. Стефанова, Д.В. Телегина, М.А. Тюменцев, А.Ж. Фурсова
[Биохимия]
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| 2021 |
Ambiguous Effects of Prolonged Dietary Supplementation with a Striatal-Enriched Protein Tyrosine Phosphatase Inhibitor, TC-2153, on a Rat Model of Sporadic Alzheimer's Disease
Ekaterina A. Rudnitskaya, Alena O. Burnyasheva, Tatiana A. Kozlova, Natalia A. Muraleva, Darya V. Telegina, Tatyana M. Khomenko, Konstantin P. Volcho, Nariman F. Salakhutdinov, Nataliya G. Kolosova
[NEUROCHEM J+]
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MEK1/2-ERK Pathway Alterations as a Therapeutic Target in Sporadic Alzheimer’s Disease: A Study in Senescence-Accelerated OXYS Rats
Natalia A. Muraleva, Nataliya G. Kolosova, Natalia A. Stefanova
[Antioxidants]
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НЕОДНОЗНАЧНЫЕ ЭФФЕКТЫ ДЛИТЕЛЬНОГО
ПРИЕМА TC-2153 – ИНГИБИТОРА СТРИАТУМСПЕЦИФИЧНОЙ
ПРОТЕИНТИРОЗИНФОСФАТАЗЫ STEP – НА МОДЕЛИ
СПОРАДИЧЕСКОЙ ФОРМЫ БОЛЕЗНИ АЛЬЦГЕЙМЕРА
Е. А. Рудницкая, А. О. Бурняшева, Т. А. Козлова, Н. А. Муралева, Д. В. Телегина,
Т. М. Хоменко, К. П. Волчо, Н. Ф. Салахутдинов, Н. Г. Колосова
[Нейрохимия]
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| 2020 |
"Single-Nucleotide
Polymorphisms (SNPs) Both Associated with Hypertension and Contributing to
Accelerated-Senescence Traits in OXYS Rats"
Vasiliy A. Devyatkin, Olga E. Redina, Natalia A. Muraleva, Nataliya G. Kolosova
[INT J MOL SCI]
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Empagliflozin, either alone or in combination with linagliptin, restores autophagy and apoptosis regulators in the kidney in db/db diabetic mice
Korbut A., Muraleva N., Taskaeva I., Bgatova N., Klimontov V.
[DIABETOLOGIA]
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Identification of Single-Nucleotide Polymorphisms in Mitochondria-Associated Genes Capable of Affecting the Development of Hypertrophic Cardiomyopathy in Senescence-Accelerated OXYS Rats
V.A.Devyatkin, N.A.Muraleva, N.G.Kolosova
[Adv. Gerontol]
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SGLT2 inhibitor empagliflozin and DPP4 inhibitor linagliptin reactivate glomerular autophagy in db/db mice, a model of type 2 diabetes
A.I. Korbut, I.S. Taskaeva, N.P. Bgatova, N.A. Muraleva, N.B. Orlov, M.V. Dashkin, A.S. Khotskina, E.L. Zavyalov, V.I. Konenkov, T. Klein, V.V. Klimontov
[INT J MOL SCI]
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Single-nucleotide polymorphisms associated with the senescence-accelerated phenotype of OXYS rats: a focus on Alzheimer’s disease-like and age-related-macular-degeneration-like pathologies
Vasiliy A. Devyatkin, Olga E. Redina, Nataliya G. Kolosova, Natalia A. Muraleva
[J ALZHEIMERS DIS]
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SkQ1 suppresses the p38 MAPK signaling pathway involved in Alzheimer’s disease-like pathology in OXYS rats
Natalia A. Muraleva, Natalia A. Stefanova and Nataliya G. Kolosova
[Antioxidants]
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| 2019 |
Rat prefrontal cortex transcriptome: effects of aging and sporadic Alzheimer’s disease-like pathology
Stefanova N.A., Ershov N.I., Maksimova K.Yi., Muraleva N.A., Tyumentsev M.A., Kolosova N.A.
[J Gerontol A Biol Sci Med Sci]
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Suppression of AMD‐Like Pathology by
Mitochondria‐Targeted Antioxidant SkQ1 Is
Associated with a Decrease in the Accumulation of
Amyloid β and in mTOR Activity
Natalia A. Muraleva, Oyuna S. Kozhevnikova, Anzhela Z. Fursova, Nataliya G. Kolosova
[Antioxidants]
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p38 MAPK-dependent alphaB-crystallin
phosphorylation in Alzheimer's disease-like pathology in OXYS rats
Muraleva NA, Kolosova NG, Stefanova NA
[EXP GERONTOL]
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Выявление однонуклеотидных полиморфизмов в ассоциированных с митохондриями генах, способных влиять на развитие гипертрофической кардиомиопатии у преждевременно стареющих крыс OXYS
В.А.Девяткин, Н.А.Муралева, Н.Г.Колосова
[Успехи геронтологии]
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Мелатонин и половое созревание рыжей (Clethrionomys Glareolus) и красно-серой (Clethrionomys Rufocanus) полевок в экспериментальных условиях
Кравченко Л.Б., Муралева Н.А.
[ZOOL ZH]
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| 2018 |
Association of the Alzheimer’s disease-like pathology development in OXYS rats with neurovascular dysfunction
Natalia A. Stefanova, Kseniya Yi. Maksimova, Ekaterina A. Rudnitskaya, Natalia A. Muraleva1, and Nataliya G. Kolosova
[BMC GENOMICS]
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Mitochondrial dysfunction as a predictor and driver of Alzheimer’s disease-like pathology in OXYS rats
Tyumentsev M, Stefanova N, Muraleva N, Rumyantseva V, Kiseleva E, Vavilin V, Kolosova N
[J ALZHEIMERS DIS]
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VEGF AND PEDF LEVELS IN THE RAT RETINA:
EFFECTS OF AGING AND AMD-LIKE RETINOPATHY
O. S. Kozhevnikova, A. Zh. Fursova, A. M. Markovets,
D. V. Telegina, N. A. Muraleva, N. G. Kolosova
[Adv. Gerontol]
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p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model
Kolosova NG, Kozhevnikova OS, Telegina DV, Fursova AZ, Stefanova NA, Muraleva NA, Venanzi F, Sherman MY, Kolesnikov SI, Sufianov AA, Gabai VL, Shneider AM.
[AGING-US]
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| 2017 |
Age-related alterations in hippocampal neurotrophin signaling pathway are involved in development and progression of Alzheimer's disease-like pathology in OXYS rats.
14. Rudnitskaya E., Muraleva N., Kolosova N., Stefanova N. Age-related alterations in hippocampal neurotrophin signaling pathway are involved in development and progression of Alzheimer's disease-like pathology in OXYS rats.
[FEBS J]
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Antioxidant SkQ1 Alleviates Signs of Alzheimer’s Disease-like Pathology in Old OXYS Rats by Reversing Mitochondrial Deterioration
Kolosova N.G., Tyumentsev M.A., Muraleva N.A., Kiseleva E.V., Vitovtov A.O., Stefanova N.A.
[CURR ALZHEIMER RES]
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Phosphorylation of αB-crystallin in the myocardium: Analysis of relations with aging and cardiomyopathy.
Muraleva NA, Devyatkin VA, Kolosova NG.
[EXP GERONTOL]
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| 2016 |
An antioxidant specifically targeting mitochondria delays progression of Alzheimer’s disease-like pathology
Natalia A. Stefanova, Natalia A. Muraleva, Kseniya Yi. Maksimova, Ekaterina A. Rudnitskaya, Elena Kiseleva, Darya V. Telegina, and Nataliya G. Kolosova
[AGING-US]
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| 2015 |
Amyloid accumulation is a late event in sporadic Alzheimer's disease-like pathology in nontransgenic rats.
Stefanova NA, Muraleva NA, Korbolina EE, Kiseleva E, Maksimova KY, Kolosova NG.
[ONCOTARGET]
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Beneficial effects of melatonin in a rat model of sporadic Alzheimer's disease.
Rudnitskaya EA, Maksimova KY, Muraleva NA, Logvinov SV, Yanshole LV, Kolosova NG, Stefanova NA.
[BIOGERONTOLOGY]
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Melatonin attenuates impairments of structural hippocampal neuroplasticity in OXYS rats during active progression of Alzheimer’s disease-like pathology
Natalia A. Stefanova, Kseniya Yi. Maksimova, Elena Kiseleva, Ekaterina A. Rudnitskaya, Natalia A. Muraleva, and Nataliya G. Kolosova
[J PINEAL RES]
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Melatonin attenuates memory impairment, amyloid beta accumulation and neurodegeneration in a rat model of sporadic Alzheimer’s disease
Ekaterina A. Rudnitskaya, Natalia A. Muraleva, Kseniya Yi. Maksimova, Elena V. Kiseleva, Nataliya G. Kolosova, and Natalia A. Stefanova
[J ALZHEIMERS DIS]
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| 2014 |
Alzheimer's Disease-Like Pathology in Senescence-Accelerated OXYS Rats can be Partially Retarded with Mitochondria-Targeted Antioxidant SkQ1.
Stefanova NA, Muraleva NA, Skulachev VP, Kolosova NG.
[J ALZHEIMERS DIS]
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Senescence-accelerated OXYS rats: A model of age-related cognitive decline with relevance to abnormalities in Alzheimer disease
Stefanova NA, Kozhevnikova OS, Vitovtov AO, Maksimova KY, Logvinov SV, Rudnitskaya EA, Korbolina EE, Muraleva NA, Kolosova NG.
[CELL CYCLE]
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The mitochondria-targeted antioxidant SkQ1 restores αB-crystallin expression and protects against AMD-like retinopathy in OXYS rats
Natalia A. Muraleva, Oyuna S. Kozhevnikova, Anna A. Zhdankina, Natalia A. Stefanova, Tatyana V. Karamysheva, Anzhella Zh. Fursova, and Nataliya G. Kolosova
[CELL CYCLE]
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| 2013 |
Association of AMD-like retinopathy development with an Alzheimer’s disease metabolic pathway in OXYS rats
Oyuna S. Kozhevnikova, Elena E. Korbolina, Natalia A. Stefanova, Natalia A. Muraleva, Yuriy L. Orlov, Nataliya G. Kolosova
[BIOGERONTOLOGY]
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Rapamycin suppresses brain aging in senescence-accelerated OXYS rats.
Kolosova NG, Vitovtov AO, Muraleva NA, Akulov AE, Stefanova NA, Blagosklonny MV.
[AGING-US]
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| 2012 |
Efficacy of glucosamine alendronate alone & in combination with dihydroquercetin for treatment of osteoporosis in animal model
Muraleva NA, Ofitserov EN, Tikhonov VP, Kolosova NG.
[INDIAN J MED RES]
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Prevention of Age-Related Macular Degeneration-Like Retinopathy by Rapamycin in Rats.
Kolosova NG, Muraleva NA, Zhdankina AA, Stefanova NA, Fursova AZ, Blagosklonny MV.
[AM J PATHOL]
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RatDNA: база данных микрочиповых исследований на крысах для генов, ассоциированных с заболеваниями старения
О.С. Кожевникова, М.К. Мартыщенко, М.А. Генаев, Е.E. Корболина, Н.А. Муралева, Н.Г. Колосова, Ю.Л. Орлов
[Vavilov journal of genetics and breeding]
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The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats
Kolosova NG, Stefanova NA, Muraleva NA, Skulachev VP.
[AGING-US]
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| 2011 |
Влияние алендроната натрия на состояние костной ткани преждевременно стареющих крыс OXYS
Муралева Н.А., Садовой М.A., Колосова Н.Г.
[Успехи геронтологии]
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| 2010 |
Особенности развития остеопороза у преждевременно стареющих крыс OXYS
Муралёва Н.А, Садовой М.А., Колосова Н.Г.
[Успехи геронтологии]
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Остеопороз как проявление генетически детерминированного синдрома преждевременного старения у крыс OXYS
Муралёва Н.А., Макеев А.А., Колосова Н.Г.
[Информационный вестник ВОГИС]
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