Andrey Akulov Department: Laboratory of High-TechnologyPhenotyping of Laboratory Animals as Genetic Models of Human Disorders Room: 4114, 7106 Email: akulov@bionet.nsc.ru Work phone: +7 (383) 363-49-63*4114, 7106

Publications

2024	Математическая модель зависимости между размерами желудочков головного мозга и капиллярным давлением у лабораторных животных А.А. Черевко, Г.С. Валова, Д.В. Петровский, А.Е. Акулов [Siberian scientific medical journal]
	Сопоставление результатов математического моделирования зависимости между размерами желудочков головного мозга и капиллярным давлением, основанного на экспериментальных и клинических данных Г.С. Валова, А.Е. Акулов, О.Б. Богомякова, А.А. Тулупов, А.А. Черевко [Siberian scientific medical journal]
2023	ОБЪЕМ ГИППОКАМПА И СПЕКТР НЕЙРОМЕТАБОЛИТОВ У ЗРЕЛЫХ СЕРЫХ КРЫС (RATTUS NORVEGICUS), СЕЛЕКЦИОНИРУЕМЫХ ПО РЕАКЦИИ НА ЧЕЛОВЕКА: ВЛИЯНИЕ РАННЕЙ СОЦИАЛЬНОЙ НЕСТАБИЛЬНОСТИ С. Г. Шихевич, А. Е. Акулов, Р. В. Кожемякина, М. П. Мошкин, Ю. Э. Гербек, Р. Г. Гулевич [Журнал эволюционной биохимии и физиологии]
2022	Challenges and Practical Solutions to MRI and Histology Matching and Measurements Using Available ImageJ Software Tools Marina Y. Khodanovich, Tatyana V. Anan’ina, Elena P. Krutenkova, Andrey E. Akulov, Marina S. Kudabaeva, Mikhail V. Svetlik, Yana A. Tumentceva, Maria M. Shadrina, Anna V. Naumova [Biomedicines]
	Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology Vadim Tseilikman, Andrey Akulov, Oleg Shevelev, Anna Khotskina, Galina Kontsevaya, Mikhail Moshkin, Julia Fedotova, Anton Pashkov, Olga Tseilikman, Eduard Agletdinov, David Tseilikman, Marina Kondashevskaya, Evgenii Zavjalov [INT J MOL SCI]
2021	Cerebral arterial architectonics and CFD simulation in mice with type 1 diabetes mellitus of diferent duration Galina Yankova, Darya Tur, Daniil Parshin, Alexander Cherevko & Andrey Akulov [SCI REP-UK]
	In Vitro 1H NMR Metabolic Profiles of Liver, Brain, and Serum in Rats After Chronic Consumption of Alcohol Mariya S. Pravdivtseva, Oleg B. Shevelev, Vadim V. Yanshole, Mikhail P. Moshkin, Igor V. Koptyug, Andrey E. Akulov [APPL MAGN RESON]
	Rational Design of Albumin Theranostic Conjugates for Gold Nanoparticles Anticancer Drugs: Where the Seed Meets the Soil? Tatyana V. Popova, Inna A. Pyshnaya, Olga D. Zakharova, Andrey E. Akulov, Oleg B. Shevelev, Julia Poletaeva, Evgenii L. Zavjalov, Vladimir N. Silnikov, Elena I. Ryabchikova and Tatyana S. Godovikova [Biomedicines]
	Sex difference feeding behaviour of NOD SCID mice in a pharmacological model of type 1 diabetes Daria A. Tur, Nikita V. Khotskin, Andrey E. Akulov [J ANIM PHYSIOL AN N]
	The Effect of Blood Contained in the Samples on the Metabolomic Profile of Mouse Brain Tissue: A Study by NMR Spectroscopy. Glinskikh A., Snytnikova O., Zelentsova E., Borisova M., Tsentalovich Y., Akulov A. [MOLECULES]
2020	Tissue-Specific Ferritin- and GFP-Based Genetic Vectors Visualize Neurons by MRI in the Intact and Post-Ischemic Rat Brain Marina Y. Khodanovich, Andrey E. Akulov, Tatyana V. Anan’ina, Marina S. Kudabaeva, Anna O. Pishchelko, Elena P. Krutenkova, Nikolay M. Nemirovich-Danchenko, Mikhail V. Svetlik, Yana A. Tumentceva, Chris Van den Haute, Rik Gijsbers, Veronique Daniëls, Irina Thiry, Alexandra G. Pershina, Maria M. Shadrina and Anna V. Naumova. [INT J MOL SCI]
2019	Quantitative Imaging of White and Gray Matter Remyelination in the Cuprizone Demyelination Model Using the Macromolecular Proton Fraction Marina Khodanovich, Anna Pishchelko, Valentina Glazacheva, Edgar Pan, Andrey Akulov, Mikhail Svetlik, Yana Tyumentseva, Tatyana Anan’ina and Vasily Yarnykh [Cells]
2018	Estimation of an area between the baseline and the effect curve parameter for lactate levels in the hippocampi of neonatal rats during anesthesia. Bannova AV, Akulov AE, Menshanov PN, Dygalo NN [J PHARMACEUT BIOMED]
	Biotin-decorated anti-cancer nucleotide theranostic conjugate of human serum albumin: Where the seed meets the soil? Popova T.V., Khan H., Chubarov A.S., Lisitskiy V.A., Antonova N.M., Akulov A.E., Shevelev O.B., Zavjalov E.L., Silnikov V.N., Ahmad S., Godovikova T.S. [BIOORG MED CHEM LETT]
	Effect of type 1 diabetes mellitus of different duration on the Willis’ circle angioarchitectonics G. S. Yankova, D. A. Tur, D. V. Parshin, A. A. Cherevko, and A. E. Akulov [AIP CONFERENCE PROCEEDINGS]
	Quantitative assessment of demyelination in ischemic stroke in vivo using macromolecular proton fraction mapping Khodanovich MY, Kisel AA, Akulov AE, Atochin DN, Kudabaeva MS, Glazacheva VY, Svetlik MV, Medvednikova YA, Mustafina LR, Yarnykh VL [J CEREBR BLOOD F MET]
	Влияние однократного введения стрептозотоцина на метаболиты гиппокампа мышей линии NODSCID Д.А. Тур, О.Б. Шевелев, М.Б. Шарапова, М.А. Золотых, А.Е. Акулов [Vavilov journal of genetics and breeding]
2017	Alteration of the brain morphology and the response to the acute stress in the recombinant mouse lines with different predisposition to catalepsy E.A. Kulikova, D.V. Bazovkina, Y.V. Antonov, A.E. Akulov, A.V. Kulikov, E.M. Kondaurova [Neuroscience Research]
	Correlations Between Neurogenesis, Oligodendrogenesis, and Myelination in the Murine Cuprizone Demyelination Model Khodanovich MY, Pishchelko AO, Glazacheva VY, Pan ES, Akulov AE, Yarnykh VL [ANN NEUROL]
	Effects of insulin-like growth factor 1 on pathologic processes in the cuprizone model of multiple sclerosis D Fedorishin, I Sorokina, T Tolstikova, A Akulov, V Glazacheva, N Nemirovich-Danchenko, M Khodanovich and V Yarnykh [JPCS]
	High-resolution three-dimensional macromolecular proton fraction mapping for quantitative neuroanatomical imaging of the rodent brain in ultra-high magnetic fields Anna V.Naumova, Andrey E.Akulov, Marina Yu.Khodanovich, Vasily L.Yarnykh [NEUROIMAGE]
	High-resolution three-dimensional quantitative map of the macromolecular proton fraction distribution in the normal rat brain Anna V.Naumova, AndreyE.Akulov, Marina Yu.Khodanovich, VasilyL.Yarnykh [Data in Brief]
	Histological validation of fast macromolecular proton fraction mapping as a quantitative myelin imaging method in the cuprizone demyelination model Marina Yu Khodanovich, Irina V. Sorokina, Valentina Yu Glazacheva, Andrey E. Akulov, Nikolay M. Nemirovich-Danchenko, Alexander V. Romashchenko, Tatyana G. Tolstikova, Lilia R. Mustafina, Vasily L. Yarnykh [SCI REP-UK]
	Macromolecular Proton Fraction (MPF) Mapping Correlates with Histologically Assessed Demyelination in the Rat Stroke Model Khodanovich MY, Kisel AA, Akulov AE, Atochin DN, Yarnykh VL [ANN NEUROL]
	Measurement of viscous flow velocity and flow visualization using two magnetic resonance imagers Boiko A.V., Akulov A.E., Chupakhin A.P., Cherevko A.A., Denisenko N.S., Savelov A.A., Stankevich Yu.A., Khe A.K., Yanchenko A.A., Tulupov A.A. [J APPL MECH TECH PH+]
	Multifunctional human serum albumin-therapeutic nucleotide conjugate with redox and pH-sensitive drug release mechanism for cancer theranostics Vladimir A. Lisitskiy, Hamda Khan, Tatyana V. Popova, Alexey S. Chubarov, Olga D. Zakharova, Andrey E. Akulov, Oleg B. Shevelev, Evgenii L. Zavjalov, Igor V. Koptyug, Mikhail P. Moshkin, Vladimir N. Silnikov, Saheem Ahmad, Tatiana S. Godovikova [BIOORG MED CHEM LETT]
	Oligodendrogenesis and neurogenesis in remyelination in the cuprizone model of multiple sclerosis: correlation with the degree of lesion A Pishchelko, M Khodanovich, E Pan, V Glazacheva, A Akulov and V Yarnykh [JPCS]
	Prospects of paramagnetic lanthanide complexes for magnetic resonance imaging, local thermosensing and diagnosing S Babailov, A Akulov, M Moshkin, I Koptyug [JPCS]
	Stress-sensitive arterial hypertension, hemodynamic changes and brain metabolites in hypertensive ISIAH rats: MRI investigation A.A. Seryapina, O.B. Shevelev, A.L. Markel, M.P. Moshkin, A.E. Akulov [EXP PHYSIOL]
	The cerebral network’s reconstruction by MRI methods and the hemodynamics study of small laboratory animal in type 1 diabetes A Akulov, A Cherevko, D Parshin, D Tur and G Yankova [JPCS]
2016	Knockout Zbtb33 gene results in an increased locomotion,exploration and pre-pulse inhibition in mice Kulikov A.V., Korostina V.S., Kulikova E.A., Fursenko D.V., Akulov A.E., Moshkin M.P.,Prokhortchouk E.B. [BEHAV BRAIN RES]
	Alterations in pharmacological and behavioural responses in recombinant mouse line with an increased predisposition to catalepsy: role of the 5-HT1A receptor E. A. Kulikova, D.V. Bazovkina, A.E. Akulov, A.S. Tsybko, D.V. Fursenko, A.V. Kulikov, V.S. Naumenko, E. Ponimaskin,* and E.M. Kondaurova [BRIT J PHARMACOL]
	Construction and investigation of 3D vessels net of the brain according to MRI data using the method of variation of scanning plane A A Cherevko, G S Yankova, S V Maltseva, D V Parshin, A E Akulov, A K Khe and A P Chupakhin [JPCS]
	Experimental measurements and visualisation of a viscous fluid flow in Y-branching modelling the common carotid artery bifurcation with MR and Doppler ultrasound velocimetry N S Denisenko, A P Chupakhin, A K Khe, A A Cherevko, A A Yanchenko, A A Tulupov, A V Boiko, A L Krivoshapkin, K Yu Orlov, M P Moshkin and A E Akulov [JPCS]
	MRI study of the cuprizone-induced mouse model of multiple sclerosis: demyelination is not found after co-treatment with polyprenols (long-chain isoprenoid alcohols) M Khodanovich, V Glazacheva, E Pan, A Akulov, E Krutenkova, V Trusov, V Yarnykh [JPCS]
	Macromolecular Proton Fraction (MPF) Mapping Strongly Correlates with Histologically Assessed White and Gray Matter Demyelination in the Murine Cuprizone Model Khodanovich MY, Sorokina IV, Glazacheva VY, Krutenkova EP, Nakesbekova AS, Romashchenko AG, Akulov AE, Tolstikova TG, Yarnykh VL. [ANN NEUROL]
	Opportunities of high-technology phenotyping by the NMR spectroscopy method by example of the metabolic response of the rat liver to the effect of alcohol and Reishi Krestina M.S., Shevelev O.B., Koptyug I.V., Gerlinskaya L.A., Peltek S.E., Akulov A.E. [Russian Journal of Genetics: Applied Research]
	Polyprenols Stimulate Neurogenesis and Reduce Demyelination in the Murine Cuprizone Model of Multiple Sclerosis Khodanovich MY, Glazacheva VY, Pan ES, Akulov AE, Krutenkova EP, Trusov VB, Yarnykh VL. [ANN NEUROL]
	Reconstruction of unbroken vasculature of mouse by varying the slope of the scan plane in MRI S Maltseva, A Cherevko, A Khe, A Akulov, A Savelov, A Tulupov, E Derevtsov, M Moshkin, A Chupakhin [JPCS]
	Study of the neuronal response to olfactory stimuli in control and LPS-stimulated mice by functional magnetic resonance imaging. Akulov A.E., Romashchenko A.V., Shevelev O.B., Petrovski D.V., Savelov A.A., Moshkin M.P. [Russian Journal of Genetics: Applied Research]
	The transfer of the main locus of catalepsy to the genome of C57Bl/6 mice produced profound alteration in the brain morphology and behavior Kulikova E.A., Bazovkina D.V., Akulov A.E., Kulikov A.V., Kondaurova E.M. [EUR NEUROPSYCHOPHARM]
	МОЛЕКУЛЯРНЫЕ ЗОНДЫ НА ОСНОВЕ ЧЕЛОВЕЧЕСКОГО СЫВОРОТОЧНОГО АЛЬБУМИНА ДЛЯ ВИЗУАЛИЗАЦИИ ОПУХОЛЕЙ МЕТОДАМИ МАГНИТНО-РЕЗОНАНСНОЙ И ФЛУОРЕСЦЕНТНОЙ ТОМОГРАФИИ А. С. Чубаров, А. Е. Акулов, О. Б. Шевелев, Е. Л. Завьялов, Т. С. Годовикова [Сибирское медицинское обозрение]
2015	Comparative study of perception and processing of socially or sexually significant odor information in male rats with normal or accelerated senescence using fMRI Tikhonova M.A., Romaschenko A.V., Akulov A.E., Ho Y.J., Kolosova N.G., Moshkin M.P., Amstislavskaya T.G. [BEHAV BRAIN RES]
	Design of protein homocystamides with enhanced tumor uptake properties for 19F magnetic resonance imaging Alexey S. Chubarov, Olga D. Zakharova, Olga A. Koval, Alexander V. Romaschenko, Andrey E. Akulov, Evgenii L. Zavjalov, Ivan A. Razumov, Igor V. Koptyug, Dmitry G. Knorre, Tatyana S. Godovikova [Bioorganic & Medicinal Chemistry]
	Macromolecular Proton Fraction (MPF) Mapping Reveals Cortical Demyelination in the Cuprizone Model Marina Yu Khodanovich, Irina V. Sorokina, Valentina Yu Glazacheva, Nikolay M. Nemirovich-Danchenko, Alexander V. Romashchenko, Andrey E. Akulov, Oleg B. Shevelev, Tatyana G. Tolstikova, Vasily L. Yarnykh. [ANN NEUROL]
	Neurometabolic Effect of Altaian Fungus Ganoderma lucidum (Reishi Mushroom) in Rats Under Moderate Alcohol Consumption Shevelev OB, Akulov AE, Dotsenko AS, Kontsevaya GV, Zolotykh MA, Gerlinskaya LA, Veprev SG, Goryachkovskaya TN, Zhukova NA, Kolchanov NA, Pel'tek SE, Moshkin MP. [ALCOHOL CLIN EXP RES]
	Reconstruction of Complex Vasculature by Varying the Slope of the Scan Plane in High-Field Magnetic Resonance Imaging Maltseva S.V., Cherevko A.A., Khe A.K., Akulov A.E., Savelov A.A., A.A. Tulupov, Derevtsov E.Yu., Moshkin M.P., Chupakhin A.P. [APPL MAGN RESON]
	The neurochemical profile of the hippocampus in isoflurane-treated and unanesthetized rat pups Menshanov PN, Akulov AE [INTERDISCIPLINARY TOXICOLOGY]
	Time-resolved volumetric MRI velocimetry of periodic flow in a carotid bifurcation (the model study) Boiko A.V., Akulov A., Chupakhin A., Cherevko A., Denisenko N., Savelov A.A., Khe A., Yanchenko A., Stankevich Y., Tulupov A. [MAGN RESON MATER PHY]
	Возможности высокотехнологичного фенотипирования методом спектроскопии ЯМР на примере метаболического отклика печени крыс на воздействие алкоголя и Рейши М.С. Крестина, О.Б. Шевелев, И.В. Коптюг, Л.А. Герлинская, С.Е. Пельтек, А.Е. Акулов [Vavilov journal of genetics and breeding]
	Исследование методом функциональной магнитно-резонансной томографии нейрональной реакции на запаховые стимулы у контрольных и ЛПС-стимулированных мышей Акулов А.Е., А.В. Ромащенко, О.Б. Шевелев, Д.В. Петровский, Савелов А.А., Мошкин М.П. [Vavilov journal of genetics and breeding]
	Магнитно-резонансная спектроскопия нейрометаболитов в гиппокампе у агрессивных и ручных самцов крыс Гулевич Р.Г., Акулов А.Е., Шихевич С.Г., Кожемякина Р.В., Плюснина И.З. [Vavilov journal of genetics and breeding]
	Сравнительное исследование трех типов протезов, изготовленных методом электроспиннинга в эксперименте in vitro и in vivo ПОПОВА И.В. СТЕПАНОВА А.О. СЕРГЕЕВИЧЕВ Д.С. АКУЛОВ А.Е. ЗАХАРОВА И.С. ПОКУШАЛОВ А.А. ЛАКТИОНОВ П.П. КАРПЕНКО А.А. [Патология кровообращения и кардиохирургия]
2014	Nasal aerodynamics protects brain and lung from inhaled dust in subterranean diggers, Ellobius talpinus M. P. Moshkin, D. V. Petrovski, A. E. Akulov, A. V. Romashchenko, L. A. Gerlinskaya, V. L. Ganimedov, M. I. Muchnaya, A. S. Sadovsky, I. V. Koptyug, A. A. Savelov, S. Yu Troitsky, Y. M. Moshkn, V. I. Bukhtiyarov, N. A. Kolchanov, R. Z. Sagdeev and V. M. Fomin [P ROY SOC B-BIOL SCI]
	Proton magnetic resonance spectroscopy of brain metabolic shifts induced by acute administration of 2-deoxy-d-glucose and lipopolysaccharides Moshkin M.P., Akulov A.E., Petrovski D.V., Saik O.V., Petrovskiy E.D., Savelov A.A., Koptyug I.V. [NMR BIOMED]
	Осаждение аэрозолей в носовых ходах норных и наземных грызунов при дыхании в запыленной среде Мошкин М.П., Петровский Д.В., Акулов А.Е., Ромащенко А.В., Герлинская Л.А., Мучная М.И., Ганимедов В.Л., Садовский А.С., Савелов А.А., Коптюг И.В., Троицкий С.Ю., Бухтияров В.И., Колчанов Н.А., Сагдеев Р.З., Фомин В.М. [Журнал Общей Биологии]
	Отбор на кататонический тип реагирования у крыс: исследование межлинейных различий методом магнитно-резонансной томографии Акулов А.Е., Алехина Т.А., Мешков И.О., Петровский Е.Д., Прокудина О.И., Коптюг И.В., Савелов А.А., Мошкин М.П. [Журнал высшей нервной деятельности]
2013	Hereditary catalepsy in mice is associated with the brain dysmorphology and altered stress response Tikhonova MA, Kulikov AV, Bazovkina DV, Kulikova EA, Tsybko AS, Bazhenova EY, Naumenko VS, Akulov AE, Moshkin MP, Popova NK. [BEHAV BRAIN RES]
	Ligand-Directed Acid-Sensitive Amidophosphate 5-Trifluoromethyl-2 '-Deoxyuridine Conjugate as a Potential Theranostic Agent Godovikova, TS ; Lisitskiy, VA ; Antonova, NM ; Popova, TV ; Zakharova, OD; Chubarov, AS ; Koptyug, IV ; Sagdeev, RZ ; Kaptein, R ; Akulov, AE ; Kaledin, VI ; Nikolin, VP ; Baiborodin, SI ; Koroleva, LS ; Silnikov, VN [BIOCONJUGATE CHEM]
	Rapamycin suppresses brain aging in senescence-accelerated OXYS rats. Kolosova NG, Vitovtov AO, Muraleva NA, Akulov AE, Stefanova NA, Blagosklonny MV. [AGING-US]
2012	Магнитно–резонансная спектроскопия метаболических изменений в мозге мышей при введении 2–дезокси–D–глюкозы и липополисахарида Мошкин М.П., Акулов А.Е., Петровский Д.В., Сайк О.В., Петровский Е.Д., Савелов А.А., Коптюг И.В. [Российский физиологический журнал имени И.М. Сеченова]
2011	Влияние малата на развитие индуцированных ротеноном изменений мозга у крыс Вистар и OXYS: МРТ исследование Колосова Н.Г., Акулов А. Е., Стефанова Н. А., Мошкин М. П., Савелов А. А., Коптюг И. В., Панов А. В., Вавилин В. А. [Doklady Akademii Nauk]
2009	Антигенная стимуляция как фактор, модулирующий социальное поведение и хемосигналы самцов лабораторных мышей Акулов А.Е., Петровский Д.В., Мошкин М.П. [Журнал высшей нервной деятельности]
	Энергетическая стоимость социального поведения мышей при активации неспецифического иммунитета Акулов А.Е., Петровский Д.В., Мошкин М.П. [Журнал Общей Биологии]